| Reaction Details |
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 | Report a problem with these data |
| Target | Adenosine receptor A3 |
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| Ligand | BDBM50236785 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1661724 (CHEMBL4011336) |
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| Ki | 1170±n/a nM |
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| Citation |  Tosh, DK; Janowsky, A; Eshleman, AJ; Warnick, E; Gao, ZG; Chen, Z; Gizewski, E; Auchampach, JA; Salvemini, D; Jacobson, KA Scaffold Repurposing of Nucleosides (Adenosine Receptor Agonists): Enhanced Activity at the Human Dopamine and Norepinephrine Sodium Symporters. J Med Chem60:3109-3123 (2017) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Adenosine receptor A3 |
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| Name: | Adenosine receptor A3 |
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| Synonyms: | A3AR | AA3R_MOUSE | Adenosine A3 receptor | Adora3 | Gpcr2 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 36460.91 |
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| Organism: | Mus musculus |
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| Description: | ChEMBL_1515686 |
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| Residue: | 319 |
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| Sequence: | MEADNTTETDWLNITYITMEAAIGLCAVVGNMLVIWVVKLNPTLRTTTVYFIVSLALADI
AVGVLVIPLAIAVSLQVKMHFYACLFMSCVLLIFTHASIMSLLAIAVHRYLRVKLTVRYR
TVTTQRRIWLFLGLCWLVSFLVGLTPMFGWNRKATLASSQNSSTLLCHFRSVVSLDYMVF
FSFITWILVPLVVMCIIYLDIFYIIRNKLSQNLTGFRETRAFYGREFKTAKSLFLVLFLF
ALCWLPLSIINFVSYFDVKIPDVAMCLGILLSHANSMMNPIVYACKIKKFKETYFLILRA
VRLCQTSDSLDSNMEQTTE
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| BDBM50236785 |
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| n/a |
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| Name | BDBM50236785 |
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| Synonyms: | CHEMBL4090355 |
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| Type | Small organic molecule |
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| Emp. Form. | C18H17ClN6O4S |
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| Mol. Mass. | 448.883 |
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| SMILES | CNC(=O)[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(NC)nc(nc12)C#Cc1ccc(Cl)s1 |r| |
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| Structure | 
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