| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Alpha-2C adrenergic receptor |
|---|
| Ligand | BDBM22541 |
|---|
| Substrate/Competitor | n/a |
|---|
| Ki | 15.85±n/a nM |
|---|
| Comments | PDSP_539 |
|---|
| Citation |  Esbenshade, TA; Krueger, KM; Miller, TR; Kang, CH; Denny, LI; Witte, DG; Yao, BB; Fox, GB; Faghih, R; Bennani, YL; Williams, M; Hancock, AA Two novel and selective nonimidazole histamine H3 receptor antagonists A-304121 and A-317920: I. In vitro pharmacological effects. J Pharmacol Exp Ther305:887-96 (2003) [PubMed] Article |
|---|
| More Info.: | Get all data from this article |
|---|
| |
| Alpha-2C adrenergic receptor |
|---|
| Name: | Alpha-2C adrenergic receptor |
|---|
| Synonyms: | ADA2C_HUMAN | ADRA2C | ADRA2L2 | ADRA2RL2 | Adrenergic alpha2C | Adrenergic receptor | Adrenergic receptor alpha | Adrenergic, alpha-2C-, receptor | Alpha-2 adrenergic receptor subtype C4 | Alpha-2C adrenoceptor | Alpha-2C adrenoreceptor | adrenergic, alpha-2C-, receptor [Homo sapiens] |
|---|
| Type: | Enzyme |
|---|
| Mol. Mass.: | 49552.32 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P18825 |
|---|
| Residue: | 462 |
|---|
| Sequence: | MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGF
LIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFG
QVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISA
VISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLR
TRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGA
LRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRR
RRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFK
FFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ
|
|
|
|---|
| BDBM22541 |
|---|
| n/a |
|---|
| Name | BDBM22541 |
|---|
| Synonyms: | Clobenpropit | N''-[(4-chlorophenyl)methyl]{[3-(1H-imidazol-5-yl)propyl]sulfanyl}methanimidamide | VUF 9153 | VUF-9153 | VUF9153 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C14H17ClN4S |
|---|
| Mol. Mass. | 308.83 |
|---|
| SMILES | NC(SCCCc1cnc[nH]1)=NCc1ccc(Cl)cc1 |w:11.12| |
|---|
| Structure | 
|
|---|
Search and Browse
