| Reaction Details |
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 | Report a problem with these data |
| Target | Fatty-acid amide hydrolase 1 [33-574] |
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| Ligand | BDBM108233 |
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| Substrate/Competitor | n/a |
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| IC50 | 4.2e+3± 1e+3 nM |
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| Citation |  Lambruschini, C; Veronesi, M; Romeo, E; Garau, G; Bandiera, T; Piomelli, D; Scarpelli, R; Dalvit, C Development of fragment-based n-FABS NMR screening applied to the membrane enzyme FAAH. Chembiochem14:1611-9 (2013) [PubMed] Article |
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| More Info.: | Get all data from this article |
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| Fatty-acid amide hydrolase 1 [33-574] |
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| Name: | Fatty-acid amide hydrolase 1 [33-574] |
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| Synonyms: | FAAH1_RAT | Faah | Faah1 | Fatty-acid amide hydrolase (rFAAH∆TM) |
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| Type: | Protein |
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| Mol. Mass.: | 59459.86 |
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| Organism: | Rattus norvegicus (Rat) |
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| Description: | 97-1722bp |
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| Residue: | 542 |
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| Sequence: | GRQKARGAATRARQKQRASLETMDKAVQRFRLQNPDLDSEALLTLPLLQLVQKLQSGELS
PEAVFFTYLGKAWEVNKGTNCVTSYLTDCETQLSQAPRQGLLYGVPVSLKECFSYKGHDS
TLGLSLNEGMPSESDCVVVQVLKLQGAVPFVHTNVPQSMLSFDCSNPLFGQTMNPWKSSK
SPGGSSGGEGALIGSGGSPLGLGTDIGGSIRFPSAFCGICGLKPTGNRLSKSGLKGCVYG
QTAVQLSLGPMARDVESLALCLKALLCEHLFTLDPTVPPLPFREEVYRSSRPLRVGYYET
DNYTMPSPAMRRALIETKQRLEAAGHTLIPFLPNNIPYALEVLSAGGLFSDGGRSFLQNF
KGDFVDPCLGDLILILRLPSWFKRLLSLLLKPLFPRLAAFLNSMRPRSAEKLWKLQHEIE
MYRQSVIAQWKAMNLDVLLTPMLGPALDLNTPGRATGAISYTVLYNCLDFPAGVVPVTTV
TAEDDAQMELYKGYFGDIWDIILKKAMKNSVGLPVAVQCVALPWQEELCLRFMREVEQLM
TP
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| BDBM108233 |
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| n/a |
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| Name | BDBM108233 |
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| Synonyms: | 1‐[2‐(trifluoromethyl)phenyl]piperazine hydrochloride (Hit 1) |
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| Type | Small organic molecule |
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| Emp. Form. | C11H13F3N2 |
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| Mol. Mass. | 230.2295 |
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| SMILES | FC(F)(F)c1ccccc1N1CCNCC1 |
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| Structure | 
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