Reaction Details |
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Target | Prostaglandin D2 receptor 2 |
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Ligand | BDBM119858 |
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Substrate/Competitor | n/a |
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Meas. Tech. | Calcium Flux Assay |
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Temperature | 310.15±n/a K |
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IC50 | 95±n/a nM |
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Comments | extracted |
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Citation | Firooznia, F; Lin, T; Mertz, E; Sidduri, A; So, S; Tilley, JW Piperidinyl naphthylacetic acids US Patent US8691993 Publication Date 4/8/2014 |
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More Info.: | Get all data from this article, Assay Method |
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Prostaglandin D2 receptor 2 |
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Name: | Prostaglandin D2 receptor 2 |
Synonyms: | CD_antigen=CD294 | CRTH2 | Chemoattractant Receptor-homologous molecule expressed on T-helper type 2 cells (CRTH2) | Chemoattractant receptor-homologous molecule expressed on Th2 cells | Chemoattractant receptor-homologous molecule expressed on Th2 cells (CRTH2) | DL1R | G protein-coupled receptor 44 | G-protein coupled receptor 44 | GPR44 | PD2R2_HUMAN | PTGDR2 | Prostaglandin D2 | Prostaglandin D2 receptor 2 | Prostaglandin D2 receptor 2 (PGD2) |
Type: | Enzyme |
Mol. Mass.: | 43295.45 |
Organism: | Homo sapiens (Human) |
Description: | Q9Y5Y4 |
Residue: | 395 |
Sequence: | MSANATLKPLCPILEQMSRLQSHSNTSIRYIDHAAVLLHGLASLLGLVENGVILFVVGCR
MRQTVVTTWVLHLALSDLLASASLPFFTYFLAVGHSWELGTTFCKLHSSIFFLNMFASGF
LLSAISLDRCLQVVRPVWAQNHRTVAAAHKVCLVLWALAVLNTVPYFVFRDTISRLDGRI
MCYYNVLLLNPGPDRDATCNSRQVALAVSKFLLAFLVPLAIIASSHAAVSLRLQHRGRRR
PGRFVRLVAAVVAAFALCWGPYHVFSLLEARAHANPGLRPLVWRGLPFVTSLAFFNSVAN
PVLYVLTCPDMLRKLRRSLRTVLESVLVDDSELGGAGSSRRRRTSSTARSASPLALCSRP
EEPRGPARLLGWLLGSCAASPQTGPLNRALSSTSS
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BDBM119858 |
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n/a |
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Name | BDBM119858 |
Synonyms: | US8691993, 7 |
Type | Small organic molecule |
Emp. Form. | C23H21ClFNO4S |
Mol. Mass. | 461.934 |
SMILES | OC(=O)Cc1cc(C2CCN(CC2)S(=O)(=O)c2cccc(Cl)c2)c2cc(F)ccc2c1 |
Structure |
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