| Reaction Details |
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 | Report a problem with these data |
| Target | Histone deacetylase 8 |
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| Ligand | BDBM120981 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Fluorometric Assay |
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| IC50 | 1270±n/a nM |
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| Citation |  Guo, L; Tang, G; Wang, Z; Wong, JC; Zhang, W N-hydroxy-benzamids for the treatment of cancer US Patent US8716285 Publication Date 5/6/2014 |
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| More Info.: | Get all data from this article, Assay Method |
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| Histone deacetylase 8 |
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| Name: | Histone deacetylase 8 |
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| Synonyms: | HD8 | HDAC8 | HDAC8_HUMAN | HDACL1 | Histone deacetylase 8 (HDAC-8) | Human HDAC8 |
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| Type: | Enzyme |
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| Mol. Mass.: | 41749.60 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Q9BY41 |
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| Residue: | 377 |
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| Sequence: | MEEPEEPADSGQSLVPVYIYSPEYVSMCDSLAKIPKRASMVHSLIEAYALHKQMRIVKPK
VASMEEMATFHTDAYLQHLQKVSQEGDDDHPDSIEYGLGYDCPATEGIFDYAAAIGGATI
TAAQCLIDGMCKVAINWSGGWHHAKKDEASGFCYLNDAVLGILRLRRKFERILYVDLDLH
HGDGVEDAFSFTSKVMTVSLHKFSPGFFPGTGDVSDVGLGKGRYYSVNVPIQDGIQDEKY
YQICESVLKEVYQAFNPKAVVLQLGADTIAGDPMCSFNMTPVGIGKCLKYILQWQLATLI
LGGGGYNLANTARCWTYLTGVILGKTLSSEIPDHEFFTAYGPDYVLEITPSCRPDRNEPH
RIQQILNYIKGNLKHVV
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| BDBM120981 |
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| n/a |
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| Name | BDBM120981 |
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| Synonyms: | US8716285, 38 |
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| Type | Small organic molecule |
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| Emp. Form. | C18H19N3O4 |
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| Mol. Mass. | 341.3612 |
|---|
| SMILES | ONC(=O)c1ccc2CCC(Cc2c1)NC(=O)OCc1cccnc1 |
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| Structure | 
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