| Reaction Details |
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 | Report a problem with these data |
| Target | Peptidyl-prolyl cis-trans isomerase A |
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| Ligand | BDBM286506 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Surface Plasmon Resonance (SPR) Assay |
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| pH | 7.4±n/a |
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| Kd | 12.7±n/a nM |
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| Comments | extracted |
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| Citation |  Fu, J; Karur, S; Li, X; Lu, P; Mergo, W; Rivkin, A; Sweeney, ZK; Tjandra, M; Weiss, A; Yifru, A Cyclic peptides and use as medicines US Patent US9566312 Publication Date 2/14/2017 |
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| More Info.: | Get all data from this article, Assay Method |
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| Peptidyl-prolyl cis-trans isomerase A |
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| Name: | Peptidyl-prolyl cis-trans isomerase A |
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| Synonyms: | CYPA | CYPA PPIase | Cyclophilin A | Cyclosporin A-binding protein | PPIA | PPIA_HUMAN | PPIase A | Peptidyl-prolyl cis-trans isomerase A | Rotamase A |
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| Type: | Protein |
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| Mol. Mass.: | 18015.32 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P62937 |
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| Residue: | 165 |
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| Sequence: | MVNPTVFFDIAVDGEPLGRVSFELFADKVPKTAENFRALSTGEKGFGYKGSCFHRIIPGF
MCQGGDFTRHNGTGGKSIYGEKFEDENFILKHTGPGILSMANAGPNTNGSQFFICTAKTE
WLDGKHVVFGKVKEGMNIVEAMERFGSRNGKTSKKITIADCGQLE
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| BDBM286506 |
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| n/a |
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| Name | BDBM286506 |
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| Synonyms: | US9566312, Compound 2.3 |
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| Type | Small organic molecule |
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| Emp. Form. | C64H113N11O13 |
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| Mol. Mass. | 1244.6479 |
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| SMILES | CCOC[C@@H](C)[C@@H]1N2CN([C@@H](C(C)C)C(=O)N(C)[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@H](C)C(=O)N(C)[C@@H](CC(C)C)C(=O)N(C)[C@@H](CC(C)C)C(=O)N(C)[C@@H](C(C)C)C(=O)N(C)[C@@H]([C@H](O)[C@H](C)C\C=C\C)C(=O)N[C@@H](CC)C(=O)N(C)[C@H](C)C2=O)C1=O |r| |
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| Structure | 
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