Reaction Details | |||
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Target | Dipeptidyl peptidase 4 [K6R,T557I] | ||
Ligand | BDBM167940 | ||
Substrate/Competitor | n/a | ||
Meas. Tech. | DPP-IV Inhibition Activity | ||
Temperature | 298.15±n/a K | ||
IC50 | 17265±0.0 nM | ||
Comments | extracted | ||
Citation | ![]() | ||
More Info.: | Get all data from this article, Assay Method | ||
Dipeptidyl peptidase 4 [K6R,T557I] | |||
Name: | Dipeptidyl peptidase 4 [K6R,T557I] | ||
Synonyms: | ADCP2 | CD26 | DPP4 | DPP4_HUMAN | Dipeptidyl peptidase IV (DPP-IV) | Dipeptidyl peptidase-IV (DDP-4) | Dipeptidyl peptidase-IV (DPP-IV) | ||
Type: | Protein | ||
Mol. Mass.: | 88325.11 | ||
Organism: | Homo sapiens (Human) | ||
Description: | P27487[K6R,T557I] | ||
Residue: | 766 | ||
Sequence: |
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BDBM167940 | |||
n/a | |||
Name | BDBM167940 | ||
Synonyms: | 6-(1,5-Dimethyl-3-oxo-2-phenyl-2,3-dihydro-1Hpyrazol-4-yl)-2-oxo-5-(phenylsulfonyl)-1,2-dihydropyridine-3-carbonitrile (24) | ||
Type | Small organic molecule | ||
Emp. Form. | C23H18N4O4S | ||
Mol. Mass. | 446.478 | ||
SMILES | Cc1c(-c2[nH]c(=O)c(cc2S(=O)(=O)c2ccccc2)C#N)c(=O)n(-c2ccccc2)n1C |(-1.38,-2.74,;.09,-3.22,;.56,-4.68,;-.34,-5.93,;.28,-7.33,;-.62,-8.58,;.01,-9.99,;-2.15,-8.42,;-2.78,-7.01,;-1.87,-5.76,;-2.5,-4.36,;-3.91,-4.98,;-1.09,-3.73,;-3.13,-2.95,;-4.66,-2.79,;-5.28,-1.38,;-4.38,-.14,;-2.85,-.3,;-2.22,-1.71,;-3.06,-9.66,;-3.96,-10.91,;2.1,-4.68,;3.01,-5.93,;2.58,-3.22,;4.04,-2.74,;4.36,-1.23,;5.83,-.76,;6.97,-1.79,;6.65,-3.29,;5.19,-3.77,;1.33,-2.31,;1.33,-.77,)| | ||
Structure | ![]() |