| Reaction Details |
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 | Report a problem with these data |
| Target | Adenosine receptor A3 |
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| Ligand | BDBM198128 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | A3 Adenosine Receptor Binding Assay |
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| pH | 7.4±n/a |
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| Temperature | 298.15±n/a K |
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| Ki | >10000±0.0 nM |
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| Comments | extracted |
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| Citation |  Cosimelli, B; Greco, G; Laneri, S; Novellino, E; Sacchi, A; Trincavelli, ML; Giacomelli, C; Taliani, S; Da Settimo, F; Martini, C 4-amino-6-alkyloxy-2-alkylthiopyrimidine derivatives as novel non-nucleoside agonists for the adenosine A1 receptor. Chem Biol Drug Des88:724-729 (2016) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Adenosine receptor A3 |
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| Name: | Adenosine receptor A3 |
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| Synonyms: | A3 adenosine receptor (hA3) | AA3R_HUMAN | ADORA3 | Adenosine A3 receptor (A3AR) |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 36197.32 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P0DMS8 |
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| Residue: | 318 |
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| Sequence: | MPNNSTALSLANVTYITMEIFIGLCAIVGNVLVICVVKLNPSLQTTTFYFIVSLALADIA
VGVLVMPLAIVVSLGITIHFYSCLFMTCLLLIFTHASIMSLLAIAVDRYLRVKLTVRYKR
VTTHRRIWLALGLCWLVSFLVGLTPMFGWNMKLTSEYHRNVTFLSCQFVSVMRMDYMVYF
SFLTWIFIPLVVMCAIYLDIFYIIRNKLSLNLSNSKETGAFYGREFKTAKSLFLVLFLFA
LSWLPLSIINCIIYFNGEVPQLVLYMGILLSHANSMMNPIVYAYKIKKFKETYLLILKAC
VVCHPSDSLDTSIEKNSE
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| BDBM198128 |
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| n/a |
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| Name | BDBM198128 |
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| Synonyms: | 4-amino-6-alkyloxy-2-benzylthiopyrimidines (5) |
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| Type | Small organic molecule |
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| Emp. Form. | C15H19N3OS |
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| Mol. Mass. | 289.396 |
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| SMILES | CC(C)COc1cc(N)nc(SCc2ccccc2)n1 |
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| Structure | 
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