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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Poly [ADP-ribose] polymerase tankyrase-1 [1091-1325] | ||
| Ligand | BDBM231069 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | Tankyrase Biochemical Assays | ||
| Temperature | 298.15±n/a K | ||
| IC50 | 4.9±n/a nM | ||
| Comments | extracted | ||
| Citation |  Bregman, H; Buchanan, JL; Chakka, N; Dimauro, EF; Gunaydin, H; Guzman-Perez, A; Hua, Z; Huang, H; Huang, X; Martin, MW; Patel, VF Oxazolidinone compounds and derivatives thereof US Patent US9340549 Publication Date 5/17/2016 | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Poly [ADP-ribose] polymerase tankyrase-1 [1091-1325] | |||
| Name: | Poly [ADP-ribose] polymerase tankyrase-1 [1091-1325] | ||
| Synonyms: | PARP5A | PARPL | TIN1 | TINF1 | TNKS | TNKS1 | TNKS1_HUMAN | Tankyrase-1 | ||
| Type: | Enzyme | ||
| Mol. Mass.: | 26714.90 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | O95271[1091-1325] | ||
| Residue: | 235 | ||
| Sequence: |
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| BDBM231069 | |||
| n/a | |||
| Name | BDBM231069 | ||
| Synonyms: | US9340549, 92 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C24H24N4O3 | ||
| Mol. Mass. | 416.4724 | ||
| SMILES | CC1(CN([C@H]2CC[C@H](CC2)n2c3ccc(cc3[nH]c2=O)C#N)C(=O)O1)c1ccccc1 |r,wU:4.3,7.10,(-4.54,5.69,;-3.2,4.92,;-2.3,3.67,;-.83,4.15,;.5,3.38,;1.83,4.15,;3.17,3.38,;3.17,1.84,;1.83,1.07,;.5,1.84,;4.5,1.07,;4.5,-.47,;3.36,-1.5,;3.68,-3.01,;5.14,-3.48,;6.28,-2.45,;5.96,-.95,;6.87,.3,;5.96,1.54,;6.73,2.88,;5.54,-4.97,;5.94,-6.46,;-.83,5.69,;.5,6.46,;-2.3,6.16,;-4.29,3.83,;-5.78,4.23,;-6.87,3.14,;-6.47,1.65,;-4.98,1.25,;-3.89,2.34,)| | ||
| Structure | 
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