Reaction Details | |||
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Target | Orexin receptor type 2 | ||
Ligand | BDBM386114 | ||
Substrate/Competitor | n/a | ||
Meas. Tech. | Measurement of Orexin Type 2 Receptor Agonist Activity | ||
EC50 | 140±n/a nM | ||
Citation | ![]() | ||
More Info.: | Get all data from this article, Assay Method | ||
Orexin receptor type 2 | |||
Name: | Orexin receptor type 2 | ||
Synonyms: | HCRTR2 | Hypocretin receptor type 2 | OX2R_HUMAN | Orexin receptor type 2 (OR 2) | Orexin receptor type 2 (OR-2) | Orexin receptor type 2 (OX2) | Orexin receptor type 2 (OX2R) | Orexin receptor type 2 (OxR2) | Ox-2-R | Ox2-R | ||
Type: | Protein | ||
Mol. Mass.: | 50710.53 | ||
Organism: | Homo sapiens (Human) | ||
Description: | O43614 | ||
Residue: | 444 | ||
Sequence: |
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BDBM386114 | |||
n/a | |||
Name | BDBM386114 | ||
Synonyms: | US10287305, Example 55 | US10508083, Example 55 | US11292766, Example 55 | methyl 4-(cis-2-(((cis-4- isopropylcyclohexyl)oxy)methyl)-3- ((methylsulfonyl)amino)piperidin-1-yl)- 4-oxobutanoate | ||
Type | Small organic molecule | ||
Emp. Form. | C21H38N2O6S | ||
Mol. Mass. | 446.601 | ||
SMILES | COC(=O)CCC(=O)N1CCC[C@H](NS(C)(=O)=O)[C@@H]1CO[C@H]1CC[C@H](CC1)C(C)C |r,wU:24.28,21.21,18.19,12.12,(-3.33,-6.54,;-3.33,-5,;-2,-4.23,;-.67,-5,;-2,-2.69,;-.67,-1.93,;.67,-2.69,;.67,-4.23,;2,-1.93,;3.33,-2.69,;4.67,-1.93,;4.67,-.38,;3.33,.38,;3.33,1.93,;4.67,2.69,;6,1.93,;3.9,4.03,;5.44,4.03,;2,-.38,;.67,.38,;.67,1.93,;-.67,2.69,;-2,1.93,;-3.33,2.69,;-3.33,4.23,;-2,5,;-.67,4.23,;-4.67,5,;-6,4.23,;-4.67,6.54,)| | ||
Structure | ![]() |