Reaction Details | |||
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Target | Interleukin-1 receptor-associated kinase 4 | ||
Ligand | BDBM380588 | ||
Substrate/Competitor | n/a | ||
Meas. Tech. | Kinase Assay | ||
IC50 | 17.0±n/a nM | ||
Citation | ![]() | ||
More Info.: | Get all data from this article, Assay Method | ||
Interleukin-1 receptor-associated kinase 4 | |||
Name: | Interleukin-1 receptor-associated kinase 4 | ||
Synonyms: | IRAK-4 | IRAK4 | IRAK4_HUMAN | Interleukin-1 receptor-associated kinase 4 (IRAK-4) | Interleukin-1 receptor-associated kinase 4 (IRAK4) | Renal carcinoma antigen NY-REN-64 | ||
Type: | Protein | ||
Mol. Mass.: | 51519.08 | ||
Organism: | Homo sapiens (Human) | ||
Description: | Q9NWZ3 | ||
Residue: | 460 | ||
Sequence: |
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BDBM380588 | |||
n/a | |||
Name | BDBM380588 | ||
Synonyms: | 2-(4-(((trans)-4-(dimethylamino)cyclohexyl)amino)quinazolin-6-yl)ethan-1-ol | US9926330, 5-1 | ||
Type | Small organic molecule | ||
Emp. Form. | C18H26N4O | ||
Mol. Mass. | 314.4252 | ||
SMILES | CN(C)[C@H]1CC[C@@H](CC1)Nc1ncnc2ccc(CCO)cc12 |r,wU:6.9,wD:3.2,(-2.67,-9.24,;-2.67,-7.7,;-4,-6.93,;-1.33,-6.93,;,-7.7,;1.33,-6.93,;1.33,-5.39,;,-4.62,;-1.33,-5.39,;2.67,-4.62,;2.67,-3.08,;1.33,-2.31,;1.33,-.77,;2.67,,;4,-.77,;5.33,,;6.67,-.77,;6.67,-2.31,;8,-3.08,;8,-4.62,;9.34,-5.39,;5.33,-3.08,;4,-2.31,)| | ||
Structure | ![]() |