| Reaction Details |
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 | Report a problem with these data |
| Target | Serine/threonine-protein kinase pim-2 |
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| Ligand | BDBM50261809 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_1696796 |
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| IC50 | >30000±n/a nM |
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| Citation |  Barberis, C; Moorcroft, N; Arendt, C; Levit, M; Moreno-Mazza, S; Batchelor, J; Mechin, I; Majid, T Discovery of N-substituted 7-azaindoles as PIM1 kinase inhibitors - Part I. Bioorg Med Chem Lett27:4730-4734 (2017) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Serine/threonine-protein kinase pim-2 |
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| Name: | Serine/threonine-protein kinase pim-2 |
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| Synonyms: | PIM2 | PIM2_HUMAN | Pim-2h | Serine/threonine-protein kinase (PIM2) | Serine/threonine-protein kinase PIM | Serine/threonine-protein kinase pim-2 (PIM2) |
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| Type: | Serine/threonine-protein kinase |
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| Mol. Mass.: | 34185.93 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Q9P1W9 |
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| Residue: | 311 |
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| Sequence: | MLTKPLQGPPAPPGTPTPPPGGKDREAFEAEYRLGPLLGKGGFGTVFAGHRLTDRLQVAI
KVIPRNRVLGWSPLSDSVTCPLEVALLWKVGAGGGHPGVIRLLDWFETQEGFMLVLERPL
PAQDLFDYITEKGPLGEGPSRCFFGQVVAAIQHCHSRGVVHRDIKDENILIDLRRGCAKL
IDFGSGALLHDEPYTDFDGTRVYSPPEWISRHQYHALPATVWSLGILLYDMVCGDIPFER
DQEILEAELHFPAHVSPDCCALIRRCLAPKPSSRPSLEEILLDPWMQTPAEDVPLNPSKG
GPAPLAWSLLP
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| BDBM50261809 |
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| n/a |
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| Name | BDBM50261809 |
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| Synonyms: | CHEMBL4098659 |
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| Type | Small organic molecule |
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| Emp. Form. | C20H22ClN5O |
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| Mol. Mass. | 383.875 |
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| SMILES | CN1CCN(CC1)c1ccc(cc1)-c1cc2c(Cl)cc(nc2n1C)C(N)=O |
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| Structure | 
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