| Reaction Details |
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 | Report a problem with these data |
| Target | Trace amine-associated receptor 1 |
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| Ligand | BDBM50292711 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1731930 (CHEMBL4147466) |
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| EC50 | 1380±n/a nM |
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| Citation |  Guariento, S; Tonelli, M; Espinoza, S; Gerasimov, AS; Gainetdinov, RR; Cichero, E Rational design, chemical synthesis and biological evaluation of novel biguanides exploring species-specificity responsiveness of TAAR1 agonists. Eur J Med Chem146:171-184 (2018) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Trace amine-associated receptor 1 |
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| Name: | Trace amine-associated receptor 1 |
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| Synonyms: | TA1 | TAAR1 | TAAR1_HUMAN | TAR1 | TRAR1 | trace amine-associated receptor 1 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 39107.47 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_792734 |
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| Residue: | 339 |
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| Sequence: | MMPFCHNIINISCVKNNWSNDVRASLYSLMVLIILTTLVGNLIVIVSISHFKQLHTPTNW
LIHSMATVDFLLGCLVMPYSMVRSAEHCWYFGEVFCKIHTSTDIMLSSASIFHLSFISID
RYYAVCDPLRYKAKMNILVICVMIFISWSVPAVFAFGMIFLELNFKGAEEIYYKHVHCRG
GCSVFFSKISGVLTFMTSFYIPGSIMLCVYYRIYLIAKEQARLISDANQKLQIGLEMKNG
ISQSKERKAVKTLGIVMGVFLICWCPFFICTVMDPFLHYIIPPTLNDVLIWFGYLNSTFN
PMVYAFFYPWFRKALKMMLFGKIFQKDSSRCKLFLELSS
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| BDBM50292711 |
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| n/a |
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| Name | BDBM50292711 |
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| Synonyms: | CHEMBL3628707 |
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| Type | Small organic molecule |
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| Emp. Form. | C12H18N6 |
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| Mol. Mass. | 246.3115 |
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| SMILES | NC(=N)NC(=N)N1CCN(CC1)c1ccccc1 |
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| Structure | 
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