| Reaction Details |
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 | Report a problem with these data |
| Target | Proteasome subunit beta type-2 |
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| Ligand | BDBM50458002 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1761589 (CHEMBL4196836) |
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| IC50 | >8000±n/a nM |
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| Citation |  Tanaka, M; Zhu, Y; Shionyu, M; Ota, N; Shibata, N; Watanabe, C; Mizusawa, A; Sasaki, R; Mizukami, T; Shiina, I; Hasegawa, M Ridaifen-F conjugated with cell-penetrating peptides inhibits intracellular proteasome activities and induces drug-resistant cell death. Eur J Med Chem146:636-650 (2018) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Proteasome subunit beta type-2 |
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| Name: | Proteasome subunit beta type-2 |
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| Synonyms: | 20S proteasome | PSB2_HUMAN | PSMB2 | Proteasome Macropain subunit |
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| Type: | PROTEIN |
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| Mol. Mass.: | 22837.53 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_1294233 |
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| Residue: | 201 |
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| Sequence: | MEYLIGIQGPDYVLVASDRVAASNIVQMKDDHDKMFKMSEKILLLCVGEAGDTVQFAEYI
QKNVQLYKMRNGYELSPTAAANFTRRNLADCLRSRTPYHVNLLLAGYDEHEGPALYYMDY
LAALAKAPFAAHGYGAFLTLSILDRYYTPTISRERAVELLRKCLEELQKRFILNLPTFSV
RIIDKNGIHDLDNISFPKQGS
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| BDBM50458002 |
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| n/a |
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| Name | BDBM50458002 |
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| Synonyms: | CHEMBL4212914 |
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| Type | Small organic molecule |
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| Emp. Form. | C52H103N33O11 |
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| Mol. Mass. | 1366.5887 |
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| SMILES | CC(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(=O)NCC(O)=O |r| |
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| Structure | 
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