| Reaction Details |
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 | Report a problem with these data |
| Target | Amine oxidase [flavin-containing] B |
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| Ligand | BDBM50281388 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1829182 (CHEMBL4329056) |
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| IC50 | 78±n/a nM |
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| Citation |  ?a?ewska, D; Olejarz-Maciej, A; Kaleta, M; Bajda, M; Siwek, A; Karcz, T; Doroz-P?onka, A; Cicho?, U; Kuder, K; Kie?-Kononowicz, K 4-tert-Pentylphenoxyalkyl derivatives - Histamine H Bioorg Med Chem Lett28:3596-3600 (2018) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Amine oxidase [flavin-containing] B |
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| Name: | Amine oxidase [flavin-containing] B |
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| Synonyms: | AOFB_HUMAN | MAO-B | MAOB | Monoamine oxidase type B | Monoamine oxidase type B (MAO B) | Monoamine oxidase type B (MAO B) | Monoamine oxidase type B (MAOB) |
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| Type: | Protein |
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| Mol. Mass.: | 58768.76 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P27338 |
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| Residue: | 520 |
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| Sequence: | MSNKCDVVVVGGGISGMAAAKLLHDSGLNVVVLEARDRVGGRTYTLRNQKVKYVDLGGSY
VGPTQNRILRLAKELGLETYKVNEVERLIHHVKGKSYPFRGPFPPVWNPITYLDHNNFWR
TMDDMGREIPSDAPWKAPLAEEWDNMTMKELLDKLCWTESAKQLATLFVNLCVTAETHEV
SALWFLWYVKQCGGTTRIISTTNGGQERKFVGGSGQVSERIMDLLGDRVKLERPVIYIDQ
TRENVLVETLNHEMYEAKYVISAIPPTLGMKIHFNPPLPMMRNQMITRVPLGSVIKCIVY
YKEPFWRKKDYCGTMIIDGEEAPVAYTLDDTKPEGNYAAIMGFILAHKARKLARLTKEER
LKKLCELYAKVLGSLEALEPVHYEEKNWCEEQYSGGCYTTYFPPGILTQYGRVLRQPVDR
IYFAGTETATHWSGYMEGAVEAGERAAREILHAMGKIPEDEIWQSEPESVDVPAQPITTT
FLERHLPSVPGLLRLIGLTTIFSATALGFLAHKRGLLVRV
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| BDBM50281388 |
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| n/a |
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| Name | BDBM50281388 |
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| Synonyms: | CHEMBL4173258 |
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| Type | Small organic molecule |
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| Emp. Form. | C22H31N3O |
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| Mol. Mass. | 353.501 |
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| SMILES | CN(CC#C)Cc1cc2cc(OCCCN3CCCCC3)ccc2n1C |
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| Structure | 
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