| Reaction Details |
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 | Report a problem with these data |
| Target | Integrase |
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| Ligand | BDBM50065794 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_90700 (CHEMBL702101) |
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| IC50 | 114000±n/a nM |
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| Citation |  Mekouar, K; Mouscadet, JF; Desmaële, D; Subra, F; Leh, H; Savouré, D; Auclair, C; d'Angelo, J Styrylquinoline derivatives: a new class of potent HIV-1 integrase inhibitors that block HIV-1 replication in CEM cells. J Med Chem41:2846-57 (1998) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Integrase |
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| Name: | Integrase |
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| Synonyms: | Human immunodeficiency virus type 1 integrase |
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| Type: | PROTEIN |
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| Mol. Mass.: | 32231.48 |
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| Organism: | Human immunodeficiency virus 1 |
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| Description: | ChEMBL_90865 |
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| Residue: | 288 |
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| Sequence: | FLDGIDKAQDEHEKYHSNWRAMASDFNLPPVVAKEIVASCDKCQLKGEAMHGQVDCSPGI
WQLDCTHLEGKVILVAVHVASGYIEAEVIPAETGQETAYFLLKLAGRWPVKTIHTDNGSN
FTSTTVKAACWWAGIKQEFGIPYNPQSQGVVESMNKELKKIIGQVRDQAEHLKTAVQMAV
FIHNFKRKGGIGGYSAGERIVDIIATDIQTKELQKQITKIQNFRVYYRDSRDPLWKGPAK
LLWKGEGAVVIQDNSDIKVVPRRKVKIIRDYGKQMAGDDCVASRQDED
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| BDBM50065794 |
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| n/a |
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| Name | BDBM50065794 |
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| Synonyms: | 8-Hydroxy-2-methyl-quinoline-7-carboxylic acid | 8-hydroxy-2-methylquinoline-7-carboxylic acid | CHEMBL39823 |
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| Type | Small organic molecule |
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| Emp. Form. | C11H9NO3 |
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| Mol. Mass. | 203.1941 |
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| SMILES | Cc1ccc2ccc(C(O)=O)c(O)c2n1 |
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| Structure | 
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