| Reaction Details |
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 | Report a problem with these data |
| Target | Guanine nucleotide binding protein, alpha q polypeptide |
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| Ligand | BDBM50468902 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1856734 (CHEMBL4357463) |
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| IC50 | 95±n/a nM |
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| Citation |  Li, J; Ge, Y; Huang, JX; Strømgaard, K; Zhang, X; Xiong, XF Heterotrimeric G Proteins as Therapeutic Targets in Drug Discovery. J Med Chem63:5013-5030 (2020) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Guanine nucleotide binding protein, alpha q polypeptide |
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| Name: | Guanine nucleotide binding protein, alpha q polypeptide |
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| Synonyms: | GNAQ | Guanine nucleotide binding protein q polypeptide |
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| Type: | PROTEIN |
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| Mol. Mass.: | 42152.56 |
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| Organism: | Cricetulus griseus |
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| Description: | ChEMBL_119059 |
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| Residue: | 359 |
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| Sequence: | MTLESIMACCLSEEAKEARRINDEIERQLRRDKRDARRELKLLLLGTGESGKSTFIKQMR
IIHGSGYSDEDKRGFTKLVYQNIFTAMQAMIRAMDTLKIPYKYEHNKAHAQLVREVDVEK
VSAFENPYVDAIKSLWNDPGIQECYDRRREYQLSDSTKYYLNDLDRVADPSYLPTQQDVL
RVRVPTTGIIEYPFDLQSVIFRMVDVGGQRSERRKWIHCFENVTSIMFLVALSEYDQVLV
ESDNENRMEESKALFRTIITYPWFQNSSVILFLNKKDLLEEKIMYSHLVDYFPEYDGPQR
DAQAAREFILKMFVDLNPDSDKIIYSHFTCATDTENIRFVFAAVKDTILQLNLKEYNLV
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| BDBM50468902 |
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| n/a |
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| Name | BDBM50468902 |
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| Synonyms: | CHEMBL4288881 |
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| Type | Small organic molecule |
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| Emp. Form. | C46H69N7O15 |
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| Mol. Mass. | 960.078 |
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| SMILES | CO[C@H](C)[C@@H]1N(C)C(=O)[C@@H](NC(=O)[C@H](C)N(C)C(=O)[C@H](C)NC(=O)C(=C)N(C)C(=O)[C@@H](Cc2ccccc2)OC(=O)[C@@H](NC(C)=O)[C@@H](C)OC1=O)[C@H](OC(=O)[C@@H](NC(C)=O)[C@H](O)C(C)C)C(C)C |r| |
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| Structure | 
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