| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Glucagon receptor |
|---|
| Ligand | BDBM50075784 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEBML_73000 |
|---|
| IC50 | 340±n/a nM |
|---|
| Citation |  de Laszlo, SE; Hacker, C; Li, B; Kim, D; MacCoss, M; Mantlo, N; Pivnichny, JV; Colwell, L; Koch, GE; Cascieri, MA; Hagmann, WK Potent, orally absorbed glucagon receptor antagonists. Bioorg Med Chem Lett9:641-6 (1999) [PubMed] |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Glucagon receptor |
|---|
| Name: | Glucagon receptor |
|---|
| Synonyms: | GL-R | GLR_MOUSE | Gcgr |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 54941.21 |
|---|
| Organism: | Mus musculus |
|---|
| Description: | ChEMBL_1338729 |
|---|
| Residue: | 485 |
|---|
| Sequence: | MPLTQLHCPHLLLLLLVLSCLPEAPSAQVMDFLFEKWKLYSDQCHHNLSLLPPPTELVCN
RTFDKYSCWPDTPPNTTANISCPWYLPWYHKVQHRLVFKRCGPDGQWVRGPRGQPWRNAS
QCQLDDEEIEVQKGVAKMYSSQQVMYTVGYSLSLGALLLALVILLGLRKLHCTRNYIHGN
LFASFVLKAGSVLVIDWLLKTRYSQKIGDDLSVSVWLSDGAMAGCRVATVIMQYGIIANY
CWLLVEGVYLYSLLSLATFSERSFFSLYLGIGWGAPLLFVIPWVVVKCLFENVQCWTSND
NMGFWWILRIPVFLALLINFFIFVHIIHLLVAKLRAHQMHYADYKFRLARSTLTLIPLLG
VHEVVFAFVTDEHAQGTLRSTKLFFDLFLSSFQGLLVAVLYCFLNKEVQAELMRRWRQWQ
EGKALQEERLASSHGSHMAPAGPCHGDPCEKLQLMSAGSSSGTGCVPSMETSLASSLPRL
ADSPT
|
|
|
|---|
| BDBM50075784 |
|---|
| n/a |
|---|
| Name | BDBM50075784 |
|---|
| Synonyms: | 4-[5-(4-Chloro-phenyl)-3-(2-hexyloxy-phenyl)-1H-pyrrol-2-yl]-pyridine | CHEMBL345834 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C27H27ClN2O |
|---|
| Mol. Mass. | 430.969 |
|---|
| SMILES | CCCCCCOc1ccccc1-c1cc([nH]c1-c1ccncc1)-c1ccc(Cl)cc1 |
|---|
| Structure | 
|
|---|
Search and Browse
