| Reaction Details |
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 | Report a problem with these data |
| Target | Mitogen-activated protein kinase 14 |
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| Ligand | BDBM50075788 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_221160 |
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| IC50 | 420±n/a nM |
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| Citation |  de Laszlo, SE; Hacker, C; Li, B; Kim, D; MacCoss, M; Mantlo, N; Pivnichny, JV; Colwell, L; Koch, GE; Cascieri, MA; Hagmann, WK Potent, orally absorbed glucagon receptor antagonists. Bioorg Med Chem Lett9:641-6 (1999) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Mitogen-activated protein kinase 14 |
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| Name: | Mitogen-activated protein kinase 14 |
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| Synonyms: | CSAID-binding protein | CSBP | CSBP1 | CSBP2 | CSPB1 | Cytokine suppressive anti-inflammatory drug-binding protein | MAP kinase 14 | MAP kinase MXI2 | MAP kinase p38 alpha | MAPK 14 | MAPK14 | MAX-interacting protein 2 | MK14_HUMAN | MXI2 | Mitogen-activated protein kinase p38 alpha | SAPK2A | Stress-activated protein kinase 2a | p38 MAP kinase alpha/beta |
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| Type: | Serine/threonine-protein kinase |
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| Mol. Mass.: | 41286.76 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Q16539 |
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| Residue: | 360 |
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| Sequence: | MSQERPTFYRQELNKTIWEVPERYQNLSPVGSGAYGSVCAAFDTKTGLRVAVKKLSRPFQ
SIIHAKRTYRELRLLKHMKHENVIGLLDVFTPARSLEEFNDVYLVTHLMGADLNNIVKCQ
KLTDDHVQFLIYQILRGLKYIHSADIIHRDLKPSNLAVNEDCELKILDFGLARHTDDEMT
GYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGRTLFPGTDHIDQLKLILRLVG
TPGAELLKKISSESARNYIQSLTQMPKMNFANVFIGANPLAVDLLEKMLVLDSDKRITAA
QALAHAYFAQYHDPDDEPVADPYDQSFESRDLLIDEWKSLTYDEVISFVPPPLDQEEMES
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| BDBM50075788 |
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| n/a |
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| Name | BDBM50075788 |
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| Synonyms: | 4-[5-(3-Chloro-phenyl)-3-(4-fluoro-phenyl)-1H-pyrrol-2-yl]-pyridine | CHEMBL160281 |
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| Type | Small organic molecule |
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| Emp. Form. | C21H14ClFN2 |
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| Mol. Mass. | 348.801 |
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| SMILES | Fc1ccc(cc1)-c1cc([nH]c1-c1ccncc1)-c1cccc(Cl)c1 |
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| Structure | 
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