| Reaction Details |
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 | Report a problem with these data |
| Target | Polyphenol oxidase 2 |
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| Ligand | BDBM197302 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1925060 (CHEMBL4428016) |
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| IC50 | 224500±n/a nM |
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| Citation |  Oyama, T; Takahashi, S; Yoshimori, A; Yamamoto, T; Sato, A; Kamiya, T; Abe, H; Abe, T; Tanuma, SI Discovery of a new type of scaffold for the creation of novel tyrosinase inhibitors. Bioorg Med Chem24:4509-4515 (2016) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Polyphenol oxidase 2 |
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| Name: | Polyphenol oxidase 2 |
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| Synonyms: | Monophenol monooxygenase | Monophenol oxidase | PPO2 | PPO2_AGABI | Tyrosinase |
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| Type: | Protein |
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| Mol. Mass.: | 63923.66 |
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| Organism: | Agaricus bisporus (Common mushroom) |
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| Description: | O42713 |
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| Residue: | 556 |
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| Sequence: | MSLIATVGPTGGVKNRLNIVDFVKNEKFFTLYVRSLELLQAKEQHDYSSFFQLAGIHGLP
FTEWAKERPSMNLYKAGYCTHGQVLFPTWHRTYLSVLEQILQGAAIEVAKKFTSNQTDWV
QAAQDLRQPYWDWGFELMPPDEVIKNEEVNITNYDGKKISVKNPILRYHFHPIDPSFKPY
GDFATWRTTVRNPDRNRREDIPGLIKKMRLEEGQIREKTYNMLKFNDAWERFSNHGISDD
QHANSLESVHDDIHVMVGYGKIEGHMDHPFFAAFDPIFWLHHTNVDRLLSLWKAINPDVW
VTSGRNRDGTMGIAPNAQINSETPLEPFYQSGDKVWTSASLADTARLGYSYPDFDKLVGG
TKELIRDAIDDLIDERYGSKPSSGARNTAFDLLADFKGITKEHKEDLKMYDWTIHVAFKK
FELKESFSLLFYFASDGGDYDQENCFVGSINAFRGTAPETCANCQDNENLIQEGFIHLNH
YLARDLESFEPQDVHKFLKEKGLSYKLYSRGDKPLTSLSVKIEGRPLHLPPGEHRPKYDH
TQARVVFDDVAVHVIN
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| BDBM197302 |
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| n/a |
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| Name | BDBM197302 |
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| Synonyms: | Benzoic acid | SAMPL4, O1 |
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| Type | Small organic molecule |
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| Emp. Form. | C7H6O2 |
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| Mol. Mass. | 122.1213 |
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| SMILES | OC(=O)c1ccccc1 |
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| Structure | 
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