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TargetAmine oxidase [flavin-containing] B
LigandBDBM50556376
Substrate/Competitorn/a
Meas. Tech.ChEMBL_2056035 (CHEMBL4711036)
IC50>1000±n/a nM
Citation Canale, VGrychowska, KKurczab, RRyng, MKeeri, ARSata?a, GOlejarz-Maciej, AKoczurkiewicz, PDrop, MBlicharz, KPiska, KP?kala, EJaniszewska, PKrawczyk, MWalczak, MChaumont-Dubel, SBojarski, AJMarin, PPopik, PZajdel, P A dual-acting 5-HT Eur J Med Chem208:0 (2020) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Amine oxidase [flavin-containing] B
Name:Amine oxidase [flavin-containing] B
Synonyms:AOFB_HUMAN | MAO-B | MAOB | Monoamine oxidase type B | Monoamine oxidase type B (MAO B) | Monoamine oxidase type B (MAO B) | Monoamine oxidase type B (MAOB)
Type:Protein
Mol. Mass.:58768.76
Organism:Homo sapiens (Human)
Description:P27338
Residue:520
Sequence:
MSNKCDVVVVGGGISGMAAAKLLHDSGLNVVVLEARDRVGGRTYTLRNQKVKYVDLGGSY
VGPTQNRILRLAKELGLETYKVNEVERLIHHVKGKSYPFRGPFPPVWNPITYLDHNNFWR
TMDDMGREIPSDAPWKAPLAEEWDNMTMKELLDKLCWTESAKQLATLFVNLCVTAETHEV
SALWFLWYVKQCGGTTRIISTTNGGQERKFVGGSGQVSERIMDLLGDRVKLERPVIYIDQ
TRENVLVETLNHEMYEAKYVISAIPPTLGMKIHFNPPLPMMRNQMITRVPLGSVIKCIVY
YKEPFWRKKDYCGTMIIDGEEAPVAYTLDDTKPEGNYAAIMGFILAHKARKLARLTKEER
LKKLCELYAKVLGSLEALEPVHYEEKNWCEEQYSGGCYTTYFPPGILTQYGRVLRQPVDR
IYFAGTETATHWSGYMEGAVEAGERAAREILHAMGKIPEDEIWQSEPESVDVPAQPITTT
FLERHLPSVPGLLRLIGLTTIFSATALGFLAHKRGLLVRV
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50556376
n/a
NameBDBM50556376
Synonyms:CHEMBL4742220
TypeSmall organic molecule
Emp. Form.C34H38N4O3S
Mol. Mass.582.756
SMILESO=S(=O)(c1ccccc1)n1ccc2c(cccc12)N1CCN(CCCCOc2cccc3C(CCc23)NCC#C)CC1
Structure
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