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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Muscarinic acetylcholine receptor M3 | ||
| Ligand | BDBM50571307 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEMBL_2114299 (CHEMBL4823149) | ||
| IC50 | 733±n/a nM | ||
| Citation |  Lanter, JC; Chen, AY; Williamson, T; Koenig, G; Blain, JF; Burnett, DA Discovery of quinuclidine modulators of cellular progranulin. Bioorg Med Chem Lett47:0 (2021) [PubMed] Article | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Muscarinic acetylcholine receptor M3 | |||
| Name: | Muscarinic acetylcholine receptor M3 | ||
| Synonyms: | ACM3_HUMAN | CHRM3 | Cholinergic, muscarinic M3 | Muscarinic Receptors M3 | Muscarinic receptor M3 | RecName: Full=Muscarinic acetylcholine receptor M3 | ||
| Type: | Enzyme | ||
| Mol. Mass.: | 66151.03 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | P20309 | ||
| Residue: | 590 | ||
| Sequence: |
| ||
| BDBM50571307 | |||
| n/a | |||
| Name | BDBM50571307 | ||
| Synonyms: | CHEMBL566204 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C23H26N2O2 | ||
| Mol. Mass. | 362.4647 | ||
| SMILES | O=C(OC1CN2CCC1CC2)N1CCc2ccccc2[C@@H]1c1ccccc1 |r,wD:20.24,THB:2:3:9.10:7.6,(23.17,-9.1,;23.17,-7.56,;21.83,-6.79,;20.48,-7.56,;20.58,-9.1,;19.2,-8.21,;17.47,-8.66,;17.48,-7.17,;19.15,-6.7,;19.48,-4.97,;19.78,-6.21,;24.49,-6.77,;24.47,-5.23,;25.82,-4.46,;27.15,-5.25,;28.48,-4.49,;29.79,-5.25,;29.79,-6.77,;28.46,-7.54,;27.15,-6.77,;25.83,-7.54,;25.83,-9.1,;24.5,-9.87,;24.52,-11.4,;25.86,-12.17,;27.18,-11.37,;27.18,-9.85,)| | ||
| Structure | 
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