| Reaction Details |
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 | Report a problem with these data |
| Target | Cannabinoid receptor 2 |
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| Ligand | BDBM50570253 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_2235841 (CHEMBL5149613) |
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| EC50 | >10000±n/a nM |
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| Citation |  Gado, F; Ferrisi, R; Polini, B; Mohamed, KA; Ricardi, C; Lucarini, E; Carpi, S; Domenichini, F; Stevenson, LA; Rapposelli, S; Saccomanni, G; Nieri, P; Ortore, G; Pertwee, RG; Ghelardini, C; Di Cesare Mannelli, L; Chiellini, G; Laprairie, RB; Manera, C Design, Synthesis, and Biological Activity of New CB2 Receptor Ligands: from Orthosteric and Allosteric Modulators to Dualsteric/Bitopic Ligands. J Med Chem65:9918-9938 (2022) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Cannabinoid receptor 2 |
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| Name: | Cannabinoid receptor 2 |
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| Synonyms: | CANNABINOID CB2 | CB-2 | CB2 | CB2A | CB2B | CNR2 | CNR2_HUMAN | CX5 | Cannabinoid CB2 receptor | Cannabinoid receptor 2 (CB2) | Cannabinoid receptor 2 (CB2R) | hCB2 |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 39690.94 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P34972 |
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| Residue: | 360 |
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| Sequence: | MEECWVTEIANGSKDGLDSNPMKDYMILSGPQKTAVAVLCTLLGLLSALENVAVLYLILS
SHQLRRKPSYLFIGSLAGADFLASVVFACSFVNFHVFHGVDSKAVFLLKIGSVTMTFTAS
VGSLLLTAIDRYLCLRYPPSYKALLTRGRALVTLGIMWVLSALVSYLPLMGWTCCPRPCS
ELFPLIPNDYLLSWLLFIAFLFSGIIYTYGHVLWKAHQHVASLSGHQDRQVPGMARMRLD
VRLAKTLGLVLAVLLICWFPVLALMAHSLATTLSDQVKKAFAFCSMLCLINSMVNPVIYA
LRSGEIRSSAHHCLAHWKKCVRGLGSEAKEEAPRSSVTETEADGKITPWPDSRDLDLSDC
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| BDBM50570253 |
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| n/a |
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| Name | BDBM50570253 |
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| Synonyms: | CHEMBL4467500 |
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| Type | Small organic molecule |
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| Emp. Form. | C21H24BrFN2O2 |
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| Mol. Mass. | 435.33 |
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| SMILES | Cc1c(Br)cn(Cc2ccc(F)cc2)c(=O)c1NC(=O)C1CCCCCC1 |
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| Structure | 
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