| Reaction Details |
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 | Report a problem with these data |
| Target | Type-1 angiotensin II receptor |
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| Ligand | BDBM50282883 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_36166 |
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| IC50 | 79±n/a nM |
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| Citation |  Levin, JI; Venkatesan, AM; Chan, PS; Bailey, TK; Vice, G; Coupet, J 6-Substituted Quinazolinone Angiotensin II Receptor Antagonists Bioorg Med Chem Lett4:1819-1824 (1994) Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Type-1 angiotensin II receptor |
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| Name: | Type-1 angiotensin II receptor |
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| Synonyms: | AGTR1 | AGTR1_BOVIN | Angiotensin II type 1a (AT-1a) receptor |
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| Type: | PROTEIN |
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| Mol. Mass.: | 41107.81 |
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| Organism: | Bos taurus |
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| Description: | ChEMBL_36779 |
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| Residue: | 359 |
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| Sequence: | MILNSSTEDGIKRIQDDCPKAGRHNYIFIMIPTLYSIIFVVGIFGNSLVVIVIYFYMKLK
TVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLLT
CLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPTIIHRNVFFIENTNITVC
AFHYESQNSTLPVGLGLTKNILGFLFPFLIILTSYTLIWKTLKKAYEIQKNKPRKDDIFK
IILAIVLFFFFSWVPHQIFTFMDVLIQLGLIRDCKIEDIVDTAMPITICLAYFNNCLNPL
FYGFLGKKFKKYFLQLLKYIPPKAKSHSNLSTKMSTLSYRPSENGNSSTKKPAPCIEVE
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| BDBM50282883 |
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| n/a |
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| Name | BDBM50282883 |
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| Synonyms: | 6-((3R,3aS,6aS)-2-Benzyl-4-oxo-hexahydro-cyclopenta[d]isoxazol-3-yl)-2-butyl-3-[2'-(1H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-3H-quinazolin-4-one | CHEMBL298509 |
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| Type | Small organic molecule |
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| Emp. Form. | C39H37N7O3 |
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| Mol. Mass. | 651.7562 |
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| SMILES | CCCCc1nc2ccc(cc2c(=O)n1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1)[C@H]1[C@H]2[C@H](CCC2=O)ON1Cc1ccccc1 |
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| Structure | 
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