| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Isocitrate lyase |
|---|
| Ligand | BDBM50276440 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_687440 (CHEMBL1292116) |
|---|
| IC50 | 318000±n/a nM |
|---|
| Citation |  Lee, YJ; Han, YR; Park, W; Nam, SH; Oh, KB; Lee, HS Synthetic analogs of indole-containing natural products as inhibitors of sortase A and isocitrate lyase. Bioorg Med Chem Lett20:6882-5 (2010) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Isocitrate lyase |
|---|
| Name: | Isocitrate lyase |
|---|
| Synonyms: | ACEA_CANAX | ICL1 |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 61398.95 |
|---|
| Organism: | Candida albicans |
|---|
| Description: | ChEMBL_972063 |
|---|
| Residue: | 550 |
|---|
| Sequence: | MPYTPIDIQKEEADFQKEVAEIKKWWSEPRWRKTKRIYSAEDIAKKRGTLKINHPSSQQA
DKLFKLLETHDADKTVSFTFGALDPIHVAQMAKYLDSIYVSGWQCSSTASTSNEPSPDLA
DYPMDTVPNKVEHLWFAQLFHDRKQREERLTLSKEERAKTPYIDFLRPIIADADTGHGGI
TAIIKLTKMFIERGAAGIHIEDQAPGTKKCGHMAGKVLVPVQEHINRLVAIRASADIFGS
NLLAVARTDSEAATLITSTIDHRDHYFIIGATNPEAGDLAALMAEAESKGIYGNELAAIE
SEWTKKAGLKLFHEAVIDEIKNGNYSNKDALIKKFTDKVNPLSHTSHKEAKKLAKELTGK
DIYFNWDVARAREGYYRYQGGTQCAVMRGRAFAPYADLIWMESALPDYAQAKEFADGVKA
AVPDQWLAYNLSPSFNWNKAMPADEQETYIKRLGKLGYVWQFITLAGLHTTALAVDDFSN
QYSQIGMKAYGQTVQQPEIEKGVEVVKHQKWSGATYIDGLLKMVSGGVTSTAAMGQGVTE
DQFKESKAKA
|
|
|
|---|
| BDBM50276440 |
|---|
| n/a |
|---|
| Name | BDBM50276440 |
|---|
| Synonyms: | CHEMBL505766 | hyrtiosin A |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C10H9NO3 |
|---|
| Mol. Mass. | 191.1834 |
|---|
| SMILES | OCC(=O)c1c[nH]c2ccc(O)cc12 |
|---|
| Structure | 
|
|---|
Search and Browse
