| Reaction Details |
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 | Report a problem with these data |
| Target | Glycogen synthase kinase-3 beta |
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| Ligand | BDBM50355911 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_775908 (CHEMBL1912881) |
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| IC50 | 1100±n/a nM |
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| Citation |  Kassis, P; Brzeszcz, J; Bénéteau, V; Lozach, O; Meijer, L; Le Guével, R; Guillouzo, C; Lewinski, K; Bourg, S; Colliandre, L; Routier, S; Mérour, JY Synthesis and biological evaluation of new 3-(6-hydroxyindol-2-yl)-5-(Phenyl) pyridine or pyrazine V-Shaped molecules as kinase inhibitors and cytotoxic agents. Eur J Med Chem46:5416-34 (2011) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Glycogen synthase kinase-3 beta |
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| Name: | Glycogen synthase kinase-3 beta |
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| Synonyms: | Glycogen synthase kinase 3 beta | Glycogen synthase kinase-3 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 46774.42 |
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| Organism: | Sus scrofa |
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| Description: | ChEMBL_939732 |
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| Residue: | 420 |
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| Sequence: | MSGRPRTTSFAESCKPVQQPSAFGSMKVSRDKDGSKVTTMVATPGQGPDRPQEVSYTDAK
VIGNGSFGVVYQAKLCDSGELVAIKKVLQDKRFKNRELQIMRKLDHCNIVRLRYFFYSSG
EKKDEVYLNLVLDYVPETVYRVARHYSRAKQTLPVIYVKLYMYQLFRSLAYIHSFGICHR
DIKPQNLLLDPDTAVLKLCDFGSAKQLVRGEPNVSYICSRYYRAPELIFGATDYTSSIDV
WSAGCVLAELLLGQPIFPGDSGVDQLVEIIKVLGTPTREQIREMNPNYTEFKFPQIKAHP
WTKVFRPRTPPEAIALCSRLLEYTPTARLTPLEACAHSFFDELRDPNVKLPNGRDTPALF
NFTTQELSSNPPLATILIPPHARIQAAASTPSNATAASDTNAGDRGQTNNTASASASNST
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| BDBM50355911 |
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| n/a |
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| Name | BDBM50355911 |
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| Synonyms: | CHEMBL1910197 |
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| Type | Small organic molecule |
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| Emp. Form. | C20H16N2O3S |
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| Mol. Mass. | 364.418 |
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| SMILES | CS(=O)(=O)c1ccc(cc1)-c1cncc(c1)-c1cc2ccc(O)cc2[nH]1 |
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| Structure | 
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