Found 39 hits with Last Name = 'brzeszcz' and Initial = 'j' Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Dual specificity tyrosine-phosphorylation-regulated kinase 1A
(RAT) | BDBM50355909
(CHEMBL1910195)Show InChI InChI=1S/C19H14N2O2/c22-16-4-1-12(2-5-16)14-7-15(11-20-10-14)18-8-13-3-6-17(23)9-19(13)21-18/h1-11,21-23H | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 60 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ d'Orl£ans
Curated by ChEMBL
| Assay Description Inhibition of rat recombinant GST-fused DYRK1A expressed in Escherichia coli using myelin protein and [33P-gamma]-ATP after 30 mins by scintillation ... |
Eur J Med Chem 46: 5416-34 (2011)
Article DOI: 10.1016/j.ejmech.2011.08.048 BindingDB Entry DOI: 10.7270/Q2T1542V |
More data for this Ligand-Target Pair | |
Cyclin-dependent kinase 5 activator 1
(Homo sapiens (Human)) | BDBM50355909
(CHEMBL1910195)Show InChI InChI=1S/C19H14N2O2/c22-16-4-1-12(2-5-16)14-7-15(11-20-10-14)18-8-13-3-6-17(23)9-19(13)21-18/h1-11,21-23H | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 160 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ d'Orl£ans
Curated by ChEMBL
| Assay Description Inhibition of human recombinant CDK5/p25 using histone H1 and [33P-gamma]-ATP after 30 mins by scintillation counting |
Eur J Med Chem 46: 5416-34 (2011)
Article DOI: 10.1016/j.ejmech.2011.08.048 BindingDB Entry DOI: 10.7270/Q2T1542V |
More data for this Ligand-Target Pair | |
Dual specificity tyrosine-phosphorylation-regulated kinase 1A
(RAT) | BDBM50355915
(CHEMBL1910201)Show InChI InChI=1S/C19H14N2O2/c22-15-3-1-12(2-4-15)13-7-8-20-18(10-13)19-11-14-9-16(23)5-6-17(14)21-19/h1-11,21-23H | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 230 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ d'Orl£ans
Curated by ChEMBL
| Assay Description Inhibition of rat recombinant GST-fused DYRK1A expressed in Escherichia coli using myelin protein and [33P-gamma]-ATP after 30 mins by scintillation ... |
Eur J Med Chem 46: 5416-34 (2011)
Article DOI: 10.1016/j.ejmech.2011.08.048 BindingDB Entry DOI: 10.7270/Q2T1542V |
More data for this Ligand-Target Pair | |
Dual specificity tyrosine-phosphorylation-regulated kinase 1A
(RAT) | BDBM50355916
(CHEMBL1910377)Show InChI InChI=1S/C19H14N2O2/c22-15-4-1-12(2-5-15)13-7-8-20-18(9-13)19-10-14-3-6-16(23)11-17(14)21-19/h1-11,21-23H | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 300 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ d'Orl£ans
Curated by ChEMBL
| Assay Description Inhibition of rat recombinant GST-fused DYRK1A expressed in Escherichia coli using myelin protein and [33P-gamma]-ATP after 30 mins by scintillation ... |
Eur J Med Chem 46: 5416-34 (2011)
Article DOI: 10.1016/j.ejmech.2011.08.048 BindingDB Entry DOI: 10.7270/Q2T1542V |
More data for this Ligand-Target Pair | |
Dual specificity tyrosine-phosphorylation-regulated kinase 1A
(RAT) | BDBM50355906
(CHEMBL1910192)Show InChI InChI=1S/C18H13N3O2/c22-13-3-1-11(2-4-13)17-9-19-10-18(21-17)16-8-12-7-14(23)5-6-15(12)20-16/h1-10,20,22-23H | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 340 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ d'Orl£ans
Curated by ChEMBL
| Assay Description Inhibition of rat recombinant GST-fused DYRK1A expressed in Escherichia coli using myelin protein and [33P-gamma]-ATP after 30 mins by scintillation ... |
Eur J Med Chem 46: 5416-34 (2011)
Article DOI: 10.1016/j.ejmech.2011.08.048 BindingDB Entry DOI: 10.7270/Q2T1542V |
More data for this Ligand-Target Pair | |
Dual specificity tyrosine-phosphorylation-regulated kinase 1A
(RAT) | BDBM50355911
(CHEMBL1910197)Show SMILES CS(=O)(=O)c1ccc(cc1)-c1cncc(c1)-c1cc2ccc(O)cc2[nH]1 Show InChI InChI=1S/C20H16N2O3S/c1-26(24,25)18-6-3-13(4-7-18)15-8-16(12-21-11-15)19-9-14-2-5-17(23)10-20(14)22-19/h2-12,22-23H,1H3 | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 350 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ d'Orl£ans
Curated by ChEMBL
| Assay Description Inhibition of rat recombinant GST-fused DYRK1A expressed in Escherichia coli using myelin protein and [33P-gamma]-ATP after 30 mins by scintillation ... |
Eur J Med Chem 46: 5416-34 (2011)
Article DOI: 10.1016/j.ejmech.2011.08.048 BindingDB Entry DOI: 10.7270/Q2T1542V |
More data for this Ligand-Target Pair | |
Cyclin-dependent kinase 5 activator 1
(Homo sapiens (Human)) | BDBM50355915
(CHEMBL1910201)Show InChI InChI=1S/C19H14N2O2/c22-15-3-1-12(2-4-15)13-7-8-20-18(10-13)19-11-14-9-16(23)5-6-17(14)21-19/h1-11,21-23H | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 360 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ d'Orl£ans
Curated by ChEMBL
| Assay Description Inhibition of human recombinant CDK5/p25 using histone H1 and [33P-gamma]-ATP after 30 mins by scintillation counting |
Eur J Med Chem 46: 5416-34 (2011)
Article DOI: 10.1016/j.ejmech.2011.08.048 BindingDB Entry DOI: 10.7270/Q2T1542V |
More data for this Ligand-Target Pair | |
Cyclin-dependent kinase 5 activator 1
(Homo sapiens (Human)) | BDBM50355911
(CHEMBL1910197)Show SMILES CS(=O)(=O)c1ccc(cc1)-c1cncc(c1)-c1cc2ccc(O)cc2[nH]1 Show InChI InChI=1S/C20H16N2O3S/c1-26(24,25)18-6-3-13(4-7-18)15-8-16(12-21-11-15)19-9-14-2-5-17(23)10-20(14)22-19/h2-12,22-23H,1H3 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 380 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ d'Orl£ans
Curated by ChEMBL
| Assay Description Inhibition of human recombinant CDK5/p25 using histone H1 and [33P-gamma]-ATP after 30 mins by scintillation counting |
Eur J Med Chem 46: 5416-34 (2011)
Article DOI: 10.1016/j.ejmech.2011.08.048 BindingDB Entry DOI: 10.7270/Q2T1542V |
More data for this Ligand-Target Pair | |
Dual specificity tyrosine-phosphorylation-regulated kinase 1A
(RAT) | BDBM50355912
(CHEMBL1910198)Show InChI InChI=1S/C18H13N3O2/c22-13-4-1-11(2-5-13)17-9-19-10-18(21-17)16-7-12-3-6-14(23)8-15(12)20-16/h1-10,20,22-23H | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 540 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ d'Orl£ans
Curated by ChEMBL
| Assay Description Inhibition of rat recombinant GST-fused DYRK1A expressed in Escherichia coli using myelin protein and [33P-gamma]-ATP after 30 mins by scintillation ... |
Eur J Med Chem 46: 5416-34 (2011)
Article DOI: 10.1016/j.ejmech.2011.08.048 BindingDB Entry DOI: 10.7270/Q2T1542V |
More data for this Ligand-Target Pair | |
Cyclin-dependent kinase 5 activator 1
(Homo sapiens (Human)) | BDBM50355916
(CHEMBL1910377)Show InChI InChI=1S/C19H14N2O2/c22-15-4-1-12(2-5-15)13-7-8-20-18(9-13)19-10-14-3-6-16(23)11-17(14)21-19/h1-11,21-23H | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 830 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ d'Orl£ans
Curated by ChEMBL
| Assay Description Inhibition of human recombinant CDK5/p25 using histone H1 and [33P-gamma]-ATP after 30 mins by scintillation counting |
Eur J Med Chem 46: 5416-34 (2011)
Article DOI: 10.1016/j.ejmech.2011.08.048 BindingDB Entry DOI: 10.7270/Q2T1542V |
More data for this Ligand-Target Pair | |
Cyclin-dependent kinase 5 activator 1
(Homo sapiens (Human)) | BDBM50355910
(CHEMBL1910196)Show SMILES Oc1ccc2cc([nH]c2c1)-c1cncc(c1)-c1ccc(cc1)C#N Show InChI InChI=1S/C20H13N3O/c21-10-13-1-3-14(4-2-13)16-7-17(12-22-11-16)19-8-15-5-6-18(24)9-20(15)23-19/h1-9,11-12,23-24H | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 900 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ d'Orl£ans
Curated by ChEMBL
| Assay Description Inhibition of human recombinant CDK5/p25 using histone H1 and [33P-gamma]-ATP after 30 mins by scintillation counting |
Eur J Med Chem 46: 5416-34 (2011)
Article DOI: 10.1016/j.ejmech.2011.08.048 BindingDB Entry DOI: 10.7270/Q2T1542V |
More data for this Ligand-Target Pair | |
Dual specificity tyrosine-phosphorylation-regulated kinase 1A
(RAT) | BDBM50355907
(CHEMBL1910193)Show SMILES Oc1ccc2[nH]c(cc2c1)-c1cncc(n1)-c1ccc(cc1)C#N Show InChI InChI=1S/C19H12N4O/c20-9-12-1-3-13(4-2-12)18-10-21-11-19(23-18)17-8-14-7-15(24)5-6-16(14)22-17/h1-8,10-11,22,24H | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ d'Orl£ans
Curated by ChEMBL
| Assay Description Inhibition of rat recombinant GST-fused DYRK1A expressed in Escherichia coli using myelin protein and [33P-gamma]-ATP after 30 mins by scintillation ... |
Eur J Med Chem 46: 5416-34 (2011)
Article DOI: 10.1016/j.ejmech.2011.08.048 BindingDB Entry DOI: 10.7270/Q2T1542V |
More data for this Ligand-Target Pair | |
Glycogen synthase kinase-3 beta
(Sus scrofa) | BDBM50355909
(CHEMBL1910195)Show InChI InChI=1S/C19H14N2O2/c22-16-4-1-12(2-5-16)14-7-15(11-20-10-14)18-8-13-3-6-17(23)9-19(13)21-18/h1-11,21-23H | PDB MMDB
Reactome pathway KEGG
UniProtKB/TrEMBL
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ d'Orl£ans
Curated by ChEMBL
| Assay Description Inhibition of porcine brain GSK3-beta assessed as incorporation of [gamma-33P]-ATP into YRRAAVPPSPSLSRHSSPHQSpEDEEE substrate after 30 mins by scinti... |
Eur J Med Chem 46: 5416-34 (2011)
Article DOI: 10.1016/j.ejmech.2011.08.048 BindingDB Entry DOI: 10.7270/Q2T1542V |
More data for this Ligand-Target Pair | |
Glycogen synthase kinase-3 beta
(Sus scrofa) | BDBM50355911
(CHEMBL1910197)Show SMILES CS(=O)(=O)c1ccc(cc1)-c1cncc(c1)-c1cc2ccc(O)cc2[nH]1 Show InChI InChI=1S/C20H16N2O3S/c1-26(24,25)18-6-3-13(4-7-18)15-8-16(12-21-11-15)19-9-14-2-5-17(23)10-20(14)22-19/h2-12,22-23H,1H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/TrEMBL
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ d'Orl£ans
Curated by ChEMBL
| Assay Description Inhibition of porcine brain GSK3-beta assessed as incorporation of [gamma-33P]-ATP into YRRAAVPPSPSLSRHSSPHQSpEDEEE substrate after 30 mins by scinti... |
Eur J Med Chem 46: 5416-34 (2011)
Article DOI: 10.1016/j.ejmech.2011.08.048 BindingDB Entry DOI: 10.7270/Q2T1542V |
More data for this Ligand-Target Pair | |
Cyclin-dependent kinase 5 activator 1
(Homo sapiens (Human)) | BDBM50355903
(CHEMBL479170)Show InChI InChI=1S/C19H14N2O2/c22-16-3-1-12(2-4-16)14-7-15(11-20-10-14)19-9-13-8-17(23)5-6-18(13)21-19/h1-11,21-23H | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ d'Orl£ans
Curated by ChEMBL
| Assay Description Inhibition of human recombinant CDK5/p25 using histone H1 and [33P-gamma]-ATP after 30 mins by scintillation counting |
Eur J Med Chem 46: 5416-34 (2011)
Article DOI: 10.1016/j.ejmech.2011.08.048 BindingDB Entry DOI: 10.7270/Q2T1542V |
More data for this Ligand-Target Pair | |
Cyclin-dependent kinase 5 activator 1
(Homo sapiens (Human)) | BDBM50355906
(CHEMBL1910192)Show InChI InChI=1S/C18H13N3O2/c22-13-3-1-11(2-4-13)17-9-19-10-18(21-17)16-8-12-7-14(23)5-6-15(12)20-16/h1-10,20,22-23H | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ d'Orl£ans
Curated by ChEMBL
| Assay Description Inhibition of human recombinant CDK5/p25 using histone H1 and [33P-gamma]-ATP after 30 mins by scintillation counting |
Eur J Med Chem 46: 5416-34 (2011)
Article DOI: 10.1016/j.ejmech.2011.08.048 BindingDB Entry DOI: 10.7270/Q2T1542V |
More data for this Ligand-Target Pair | |
Cyclin-dependent kinase 5 activator 1
(Homo sapiens (Human)) | BDBM50355912
(CHEMBL1910198)Show InChI InChI=1S/C18H13N3O2/c22-13-4-1-11(2-5-13)17-9-19-10-18(21-17)16-7-12-3-6-14(23)8-15(12)20-16/h1-10,20,22-23H | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ d'Orl£ans
Curated by ChEMBL
| Assay Description Inhibition of human recombinant CDK5/p25 using histone H1 and [33P-gamma]-ATP after 30 mins by scintillation counting |
Eur J Med Chem 46: 5416-34 (2011)
Article DOI: 10.1016/j.ejmech.2011.08.048 BindingDB Entry DOI: 10.7270/Q2T1542V |
More data for this Ligand-Target Pair | |
Dual specificity tyrosine-phosphorylation-regulated kinase 1A
(RAT) | BDBM50355910
(CHEMBL1910196)Show SMILES Oc1ccc2cc([nH]c2c1)-c1cncc(c1)-c1ccc(cc1)C#N Show InChI InChI=1S/C20H13N3O/c21-10-13-1-3-14(4-2-13)16-7-17(12-22-11-16)19-8-15-5-6-18(24)9-20(15)23-19/h1-9,11-12,23-24H | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ d'Orl£ans
Curated by ChEMBL
| Assay Description Inhibition of rat recombinant GST-fused DYRK1A expressed in Escherichia coli using myelin protein and [33P-gamma]-ATP after 30 mins by scintillation ... |
Eur J Med Chem 46: 5416-34 (2011)
Article DOI: 10.1016/j.ejmech.2011.08.048 BindingDB Entry DOI: 10.7270/Q2T1542V |
More data for this Ligand-Target Pair | |
Cyclin-dependent kinase 5 activator 1
(Homo sapiens (Human)) | BDBM50355905
(CHEMBL1910191)Show SMILES CS(=O)(=O)c1ccc(cc1)-c1cncc(c1)-c1cc2cc(O)ccc2[nH]1 Show InChI InChI=1S/C20H16N2O3S/c1-26(24,25)18-5-2-13(3-6-18)15-8-16(12-21-11-15)20-10-14-9-17(23)4-7-19(14)22-20/h2-12,22-23H,1H3 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ d'Orl£ans
Curated by ChEMBL
| Assay Description Inhibition of human recombinant CDK5/p25 using histone H1 and [33P-gamma]-ATP after 30 mins by scintillation counting |
Eur J Med Chem 46: 5416-34 (2011)
Article DOI: 10.1016/j.ejmech.2011.08.048 BindingDB Entry DOI: 10.7270/Q2T1542V |
More data for this Ligand-Target Pair | |
Dual specificity tyrosine-phosphorylation-regulated kinase 1A
(RAT) | BDBM50355905
(CHEMBL1910191)Show SMILES CS(=O)(=O)c1ccc(cc1)-c1cncc(c1)-c1cc2cc(O)ccc2[nH]1 Show InChI InChI=1S/C20H16N2O3S/c1-26(24,25)18-5-2-13(3-6-18)15-8-16(12-21-11-15)20-10-14-9-17(23)4-7-19(14)22-20/h2-12,22-23H,1H3 | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 2.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ d'Orl£ans
Curated by ChEMBL
| Assay Description Inhibition of rat recombinant GST-fused DYRK1A expressed in Escherichia coli using myelin protein and [33P-gamma]-ATP after 30 mins by scintillation ... |
Eur J Med Chem 46: 5416-34 (2011)
Article DOI: 10.1016/j.ejmech.2011.08.048 BindingDB Entry DOI: 10.7270/Q2T1542V |
More data for this Ligand-Target Pair | |
Glycogen synthase kinase-3 beta
(Sus scrofa) | BDBM50355914
(CHEMBL1910200)Show SMILES CS(=O)(=O)c1ccc(cc1)-c1cncc(n1)-c1cc2ccc(O)cc2[nH]1 Show InChI InChI=1S/C19H15N3O3S/c1-26(24,25)15-6-3-12(4-7-15)18-10-20-11-19(22-18)17-8-13-2-5-14(23)9-16(13)21-17/h2-11,21,23H,1H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/TrEMBL
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 2.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ d'Orl£ans
Curated by ChEMBL
| Assay Description Inhibition of porcine brain GSK3-beta assessed as incorporation of [gamma-33P]-ATP into YRRAAVPPSPSLSRHSSPHQSpEDEEE substrate after 30 mins by scinti... |
Eur J Med Chem 46: 5416-34 (2011)
Article DOI: 10.1016/j.ejmech.2011.08.048 BindingDB Entry DOI: 10.7270/Q2T1542V |
More data for this Ligand-Target Pair | |
Cyclin-dependent kinase 5 activator 1
(Homo sapiens (Human)) | BDBM50355914
(CHEMBL1910200)Show SMILES CS(=O)(=O)c1ccc(cc1)-c1cncc(n1)-c1cc2ccc(O)cc2[nH]1 Show InChI InChI=1S/C19H15N3O3S/c1-26(24,25)15-6-3-12(4-7-15)18-10-20-11-19(22-18)17-8-13-2-5-14(23)9-16(13)21-17/h2-11,21,23H,1H3 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 2.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ d'Orl£ans
Curated by ChEMBL
| Assay Description Inhibition of human recombinant CDK5/p25 using histone H1 and [33P-gamma]-ATP after 30 mins by scintillation counting |
Eur J Med Chem 46: 5416-34 (2011)
Article DOI: 10.1016/j.ejmech.2011.08.048 BindingDB Entry DOI: 10.7270/Q2T1542V |
More data for this Ligand-Target Pair | |
Dual specificity tyrosine-phosphorylation-regulated kinase 1A
(RAT) | BDBM50355914
(CHEMBL1910200)Show SMILES CS(=O)(=O)c1ccc(cc1)-c1cncc(n1)-c1cc2ccc(O)cc2[nH]1 Show InChI InChI=1S/C19H15N3O3S/c1-26(24,25)15-6-3-12(4-7-15)18-10-20-11-19(22-18)17-8-13-2-5-14(23)9-16(13)21-17/h2-11,21,23H,1H3 | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 2.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ d'Orl£ans
Curated by ChEMBL
| Assay Description Inhibition of rat recombinant GST-fused DYRK1A expressed in Escherichia coli using myelin protein and [33P-gamma]-ATP after 30 mins by scintillation ... |
Eur J Med Chem 46: 5416-34 (2011)
Article DOI: 10.1016/j.ejmech.2011.08.048 BindingDB Entry DOI: 10.7270/Q2T1542V |
More data for this Ligand-Target Pair | |
Dual specificity tyrosine-phosphorylation-regulated kinase 1A
(RAT) | BDBM50355908
(CHEMBL1910194)Show SMILES CS(=O)(=O)c1ccc(cc1)-c1cncc(n1)-c1cc2cc(O)ccc2[nH]1 Show InChI InChI=1S/C19H15N3O3S/c1-26(24,25)15-5-2-12(3-6-15)18-10-20-11-19(22-18)17-9-13-8-14(23)4-7-16(13)21-17/h2-11,21,23H,1H3 | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 3.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ d'Orl£ans
Curated by ChEMBL
| Assay Description Inhibition of rat recombinant GST-fused DYRK1A expressed in Escherichia coli using myelin protein and [33P-gamma]-ATP after 30 mins by scintillation ... |
Eur J Med Chem 46: 5416-34 (2011)
Article DOI: 10.1016/j.ejmech.2011.08.048 BindingDB Entry DOI: 10.7270/Q2T1542V |
More data for this Ligand-Target Pair | |
Dual specificity tyrosine-phosphorylation-regulated kinase 1A
(RAT) | BDBM50355904
(CHEMBL1910190)Show SMILES Oc1ccc2[nH]c(cc2c1)-c1cncc(c1)-c1ccc(cc1)C#N Show InChI InChI=1S/C20H13N3O/c21-10-13-1-3-14(4-2-13)16-7-17(12-22-11-16)20-9-15-8-18(24)5-6-19(15)23-20/h1-9,11-12,23-24H | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 3.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ d'Orl£ans
Curated by ChEMBL
| Assay Description Inhibition of rat recombinant GST-fused DYRK1A expressed in Escherichia coli using myelin protein and [33P-gamma]-ATP after 30 mins by scintillation ... |
Eur J Med Chem 46: 5416-34 (2011)
Article DOI: 10.1016/j.ejmech.2011.08.048 BindingDB Entry DOI: 10.7270/Q2T1542V |
More data for this Ligand-Target Pair | |
Glycogen synthase kinase-3 beta
(Sus scrofa) | BDBM50355910
(CHEMBL1910196)Show SMILES Oc1ccc2cc([nH]c2c1)-c1cncc(c1)-c1ccc(cc1)C#N Show InChI InChI=1S/C20H13N3O/c21-10-13-1-3-14(4-2-13)16-7-17(12-22-11-16)19-8-15-5-6-18(24)9-20(15)23-19/h1-9,11-12,23-24H | PDB MMDB
Reactome pathway KEGG
UniProtKB/TrEMBL
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 4.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ d'Orl£ans
Curated by ChEMBL
| Assay Description Inhibition of porcine brain GSK3-beta assessed as incorporation of [gamma-33P]-ATP into YRRAAVPPSPSLSRHSSPHQSpEDEEE substrate after 30 mins by scinti... |
Eur J Med Chem 46: 5416-34 (2011)
Article DOI: 10.1016/j.ejmech.2011.08.048 BindingDB Entry DOI: 10.7270/Q2T1542V |
More data for this Ligand-Target Pair | |
Cyclin-dependent kinase 5 activator 1
(Homo sapiens (Human)) | BDBM50355907
(CHEMBL1910193)Show SMILES Oc1ccc2[nH]c(cc2c1)-c1cncc(n1)-c1ccc(cc1)C#N Show InChI InChI=1S/C19H12N4O/c20-9-12-1-3-13(4-2-12)18-10-21-11-19(23-18)17-8-14-7-15(24)5-6-16(14)22-17/h1-8,10-11,22,24H | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 4.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ d'Orl£ans
Curated by ChEMBL
| Assay Description Inhibition of human recombinant CDK5/p25 using histone H1 and [33P-gamma]-ATP after 30 mins by scintillation counting |
Eur J Med Chem 46: 5416-34 (2011)
Article DOI: 10.1016/j.ejmech.2011.08.048 BindingDB Entry DOI: 10.7270/Q2T1542V |
More data for this Ligand-Target Pair | |
Glycogen synthase kinase-3 beta
(Sus scrofa) | BDBM50355906
(CHEMBL1910192)Show InChI InChI=1S/C18H13N3O2/c22-13-3-1-11(2-4-13)17-9-19-10-18(21-17)16-8-12-7-14(23)5-6-15(12)20-16/h1-10,20,22-23H | PDB MMDB
Reactome pathway KEGG
UniProtKB/TrEMBL
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 4.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ d'Orl£ans
Curated by ChEMBL
| Assay Description Inhibition of porcine brain GSK3-beta assessed as incorporation of [gamma-33P]-ATP into YRRAAVPPSPSLSRHSSPHQSpEDEEE substrate after 30 mins by scinti... |
Eur J Med Chem 46: 5416-34 (2011)
Article DOI: 10.1016/j.ejmech.2011.08.048 BindingDB Entry DOI: 10.7270/Q2T1542V |
More data for this Ligand-Target Pair | |
Dual specificity tyrosine-phosphorylation-regulated kinase 1A
(RAT) | BDBM50355913
(CHEMBL1910199)Show SMILES Oc1ccc2cc([nH]c2c1)-c1cncc(n1)-c1ccc(cc1)C#N Show InChI InChI=1S/C19H12N4O/c20-9-12-1-3-13(4-2-12)18-10-21-11-19(23-18)17-7-14-5-6-15(24)8-16(14)22-17/h1-8,10-11,22,24H | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 5.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ d'Orl£ans
Curated by ChEMBL
| Assay Description Inhibition of rat recombinant GST-fused DYRK1A expressed in Escherichia coli using myelin protein and [33P-gamma]-ATP after 30 mins by scintillation ... |
Eur J Med Chem 46: 5416-34 (2011)
Article DOI: 10.1016/j.ejmech.2011.08.048 BindingDB Entry DOI: 10.7270/Q2T1542V |
More data for this Ligand-Target Pair | |
Glycogen synthase kinase-3 beta
(Sus scrofa) | BDBM50355912
(CHEMBL1910198)Show InChI InChI=1S/C18H13N3O2/c22-13-4-1-11(2-5-13)17-9-19-10-18(21-17)16-7-12-3-6-14(23)8-15(12)20-16/h1-10,20,22-23H | PDB MMDB
Reactome pathway KEGG
UniProtKB/TrEMBL
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 5.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ d'Orl£ans
Curated by ChEMBL
| Assay Description Inhibition of porcine brain GSK3-beta assessed as incorporation of [gamma-33P]-ATP into YRRAAVPPSPSLSRHSSPHQSpEDEEE substrate after 30 mins by scinti... |
Eur J Med Chem 46: 5416-34 (2011)
Article DOI: 10.1016/j.ejmech.2011.08.048 BindingDB Entry DOI: 10.7270/Q2T1542V |
More data for this Ligand-Target Pair | |
Cyclin-dependent kinase 5 activator 1
(Homo sapiens (Human)) | BDBM50355904
(CHEMBL1910190)Show SMILES Oc1ccc2[nH]c(cc2c1)-c1cncc(c1)-c1ccc(cc1)C#N Show InChI InChI=1S/C20H13N3O/c21-10-13-1-3-14(4-2-13)16-7-17(12-22-11-16)20-9-15-8-18(24)5-6-19(15)23-20/h1-9,11-12,23-24H | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 5.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ d'Orl£ans
Curated by ChEMBL
| Assay Description Inhibition of human recombinant CDK5/p25 using histone H1 and [33P-gamma]-ATP after 30 mins by scintillation counting |
Eur J Med Chem 46: 5416-34 (2011)
Article DOI: 10.1016/j.ejmech.2011.08.048 BindingDB Entry DOI: 10.7270/Q2T1542V |
More data for this Ligand-Target Pair | |
Cyclin-dependent kinase 5 activator 1
(Homo sapiens (Human)) | BDBM50355913
(CHEMBL1910199)Show SMILES Oc1ccc2cc([nH]c2c1)-c1cncc(n1)-c1ccc(cc1)C#N Show InChI InChI=1S/C19H12N4O/c20-9-12-1-3-13(4-2-12)18-10-21-11-19(23-18)17-7-14-5-6-15(24)8-16(14)22-17/h1-8,10-11,22,24H | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 5.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ d'Orl£ans
Curated by ChEMBL
| Assay Description Inhibition of human recombinant CDK5/p25 using histone H1 and [33P-gamma]-ATP after 30 mins by scintillation counting |
Eur J Med Chem 46: 5416-34 (2011)
Article DOI: 10.1016/j.ejmech.2011.08.048 BindingDB Entry DOI: 10.7270/Q2T1542V |
More data for this Ligand-Target Pair | |
Glycogen synthase kinase-3 beta
(Sus scrofa) | BDBM50355913
(CHEMBL1910199)Show SMILES Oc1ccc2cc([nH]c2c1)-c1cncc(n1)-c1ccc(cc1)C#N Show InChI InChI=1S/C19H12N4O/c20-9-12-1-3-13(4-2-12)18-10-21-11-19(23-18)17-7-14-5-6-15(24)8-16(14)22-17/h1-8,10-11,22,24H | PDB MMDB
Reactome pathway KEGG
UniProtKB/TrEMBL
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 5.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ d'Orl£ans
Curated by ChEMBL
| Assay Description Inhibition of porcine brain GSK3-beta assessed as incorporation of [gamma-33P]-ATP into YRRAAVPPSPSLSRHSSPHQSpEDEEE substrate after 30 mins by scinti... |
Eur J Med Chem 46: 5416-34 (2011)
Article DOI: 10.1016/j.ejmech.2011.08.048 BindingDB Entry DOI: 10.7270/Q2T1542V |
More data for this Ligand-Target Pair | |
Cyclin-dependent kinase 5 activator 1
(Homo sapiens (Human)) | BDBM50355908
(CHEMBL1910194)Show SMILES CS(=O)(=O)c1ccc(cc1)-c1cncc(n1)-c1cc2cc(O)ccc2[nH]1 Show InChI InChI=1S/C19H15N3O3S/c1-26(24,25)15-5-2-12(3-6-15)18-10-20-11-19(22-18)17-9-13-8-14(23)4-7-16(13)21-17/h2-11,21,23H,1H3 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 6.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ d'Orl£ans
Curated by ChEMBL
| Assay Description Inhibition of human recombinant CDK5/p25 using histone H1 and [33P-gamma]-ATP after 30 mins by scintillation counting |
Eur J Med Chem 46: 5416-34 (2011)
Article DOI: 10.1016/j.ejmech.2011.08.048 BindingDB Entry DOI: 10.7270/Q2T1542V |
More data for this Ligand-Target Pair | |
Glycogen synthase kinase-3 beta
(Sus scrofa) | BDBM50355905
(CHEMBL1910191)Show SMILES CS(=O)(=O)c1ccc(cc1)-c1cncc(c1)-c1cc2cc(O)ccc2[nH]1 Show InChI InChI=1S/C20H16N2O3S/c1-26(24,25)18-5-2-13(3-6-18)15-8-16(12-21-11-15)20-10-14-9-17(23)4-7-19(14)22-20/h2-12,22-23H,1H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/TrEMBL
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 7.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ d'Orl£ans
Curated by ChEMBL
| Assay Description Inhibition of porcine brain GSK3-beta assessed as incorporation of [gamma-33P]-ATP into YRRAAVPPSPSLSRHSSPHQSpEDEEE substrate after 30 mins by scinti... |
Eur J Med Chem 46: 5416-34 (2011)
Article DOI: 10.1016/j.ejmech.2011.08.048 BindingDB Entry DOI: 10.7270/Q2T1542V |
More data for this Ligand-Target Pair | |
Glycogen synthase kinase-3 beta
(Sus scrofa) | BDBM50355907
(CHEMBL1910193)Show SMILES Oc1ccc2[nH]c(cc2c1)-c1cncc(n1)-c1ccc(cc1)C#N Show InChI InChI=1S/C19H12N4O/c20-9-12-1-3-13(4-2-12)18-10-21-11-19(23-18)17-8-14-7-15(24)5-6-16(14)22-17/h1-8,10-11,22,24H | PDB MMDB
Reactome pathway KEGG
UniProtKB/TrEMBL
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 2.60E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ d'Orl£ans
Curated by ChEMBL
| Assay Description Inhibition of porcine brain GSK3-beta assessed as incorporation of [gamma-33P]-ATP into YRRAAVPPSPSLSRHSSPHQSpEDEEE substrate after 30 mins by scinti... |
Eur J Med Chem 46: 5416-34 (2011)
Article DOI: 10.1016/j.ejmech.2011.08.048 BindingDB Entry DOI: 10.7270/Q2T1542V |
More data for this Ligand-Target Pair | |
Glycogen synthase kinase-3 beta
(Sus scrofa) | BDBM50355908
(CHEMBL1910194)Show SMILES CS(=O)(=O)c1ccc(cc1)-c1cncc(n1)-c1cc2cc(O)ccc2[nH]1 Show InChI InChI=1S/C19H15N3O3S/c1-26(24,25)15-5-2-12(3-6-15)18-10-20-11-19(22-18)17-9-13-8-14(23)4-7-16(13)21-17/h2-11,21,23H,1H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/TrEMBL
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 2.60E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ d'Orl£ans
Curated by ChEMBL
| Assay Description Inhibition of porcine brain GSK3-beta assessed as incorporation of [gamma-33P]-ATP into YRRAAVPPSPSLSRHSSPHQSpEDEEE substrate after 30 mins by scinti... |
Eur J Med Chem 46: 5416-34 (2011)
Article DOI: 10.1016/j.ejmech.2011.08.048 BindingDB Entry DOI: 10.7270/Q2T1542V |
More data for this Ligand-Target Pair | |
Glycogen synthase kinase-3 beta
(Sus scrofa) | BDBM50355903
(CHEMBL479170)Show InChI InChI=1S/C19H14N2O2/c22-16-3-1-12(2-4-16)14-7-15(11-20-10-14)19-9-13-8-17(23)5-6-18(13)21-19/h1-11,21-23H | PDB MMDB
Reactome pathway KEGG
UniProtKB/TrEMBL
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 4.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ d'Orl£ans
Curated by ChEMBL
| Assay Description Inhibition of porcine brain GSK3-beta assessed as incorporation of [gamma-33P]-ATP into YRRAAVPPSPSLSRHSSPHQSpEDEEE substrate after 30 mins by scinti... |
Eur J Med Chem 46: 5416-34 (2011)
Article DOI: 10.1016/j.ejmech.2011.08.048 BindingDB Entry DOI: 10.7270/Q2T1542V |
More data for this Ligand-Target Pair | |
Glycogen synthase kinase-3 beta
(Sus scrofa) | BDBM50355904
(CHEMBL1910190)Show SMILES Oc1ccc2[nH]c(cc2c1)-c1cncc(c1)-c1ccc(cc1)C#N Show InChI InChI=1S/C20H13N3O/c21-10-13-1-3-14(4-2-13)16-7-17(12-22-11-16)20-9-15-8-18(24)5-6-19(15)23-20/h1-9,11-12,23-24H | PDB MMDB
Reactome pathway KEGG
UniProtKB/TrEMBL
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ d'Orl£ans
Curated by ChEMBL
| Assay Description Inhibition of porcine brain GSK3-beta assessed as incorporation of [gamma-33P]-ATP into YRRAAVPPSPSLSRHSSPHQSpEDEEE substrate after 30 mins by scinti... |
Eur J Med Chem 46: 5416-34 (2011)
Article DOI: 10.1016/j.ejmech.2011.08.048 BindingDB Entry DOI: 10.7270/Q2T1542V |
More data for this Ligand-Target Pair | |