| Reaction Details |
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 | Report a problem with these data |
| Target | Melanocortin receptor 4 |
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| Ligand | BDBM50134493 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_106190 |
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| EC50 | 520±n/a nM |
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| Citation |  Dyck, B; Parker, J; Phillips, T; Carter, L; Murphy, B; Summers, R; Hermann, J; Baker, T; Cismowski, M; Saunders, J; Goodfellow, V Aryl piperazine melanocortin MC4 receptor agonists. Bioorg Med Chem Lett13:3793-6 (2003) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Melanocortin receptor 4 |
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| Name: | Melanocortin receptor 4 |
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| Synonyms: | MC4-R | MC4R | MC4R_HUMAN | Melanocortin MC4 | Melanocortin receptor 4 (MC-4) | Melanocortin receptor 4 (MC4-R) | Melanocortin receptor 4 (MC4R) |
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| Type: | Enzyme |
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| Mol. Mass.: | 36949.50 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P32245 |
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| Residue: | 332 |
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| Sequence: | MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLL
ENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVN
IDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVS
GILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGAN
MKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPL
IYALRSQELRKTFKEIICCYPLGGLCDLSSRY
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| BDBM50134493 |
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| n/a |
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| Name | BDBM50134493 |
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| Synonyms: | (R)-1,2,3,4-Tetrahydro-isoquinoline-3-carboxylic acid ((R)-1-(4-chloro-benzyl)-2-{4-[2-(methanesulfonyl-methyl-amino)-phenyl]-piperazin-1-yl}-2-oxo-ethyl)-amide | CHEMBL338277 |
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| Type | Small organic molecule |
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| Emp. Form. | C31H36ClN5O4S |
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| Mol. Mass. | 610.167 |
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| SMILES | CN(c1ccccc1N1CCN(CC1)C(=O)[C@@H](Cc1ccc(Cl)cc1)NC(=O)[C@H]1Cc2ccccc2CN1)S(C)(=O)=O |
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| Structure | 
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