| Reaction Details |
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 | Report a problem with these data |
| Target | Probable G-protein coupled receptor 142 |
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| Ligand | BDBM50390577 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_835427 (CHEMBL2072133) |
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| EC50 | 1400±n/a nM |
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| Citation |  Lizarzaburu, M; Turcotte, S; Du, X; Duquette, J; Fu, A; Houze, J; Li, L; Liu, J; Murakoshi, M; Oda, K; Okuyama, R; Nara, F; Reagan, J; Yu, M; Medina, JC Discovery and optimization of a novel series of GPR142 agonists for the treatment of type 2 diabetes mellitus. Bioorg Med Chem Lett22:5942-7 (2012) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Probable G-protein coupled receptor 142 |
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| Name: | Probable G-protein coupled receptor 142 |
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| Synonyms: | GP142_MOUSE | Gpr142 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 40779.27 |
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| Organism: | Mus musculus |
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| Description: | ChEMBL_985965 |
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| Residue: | 365 |
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| Sequence: | MHLNSNPNSYICDAYQHADLLWSLSPHVLTKAVQPQVTLLPTVNGSNPRYDGVDGHWPES
PERSPCVAGIIPVIYYSVLLSLGLPVALARLAARTRKPSYHYLLALTASDIVTQVIIVFV
GFLLQGAVLARQVPQAVVRTANILEFAANHASVWIAVLFTVDRYNALCRPLRHRATSSPG
RTHRAIAAVIGVTLLTGIPFYWWLDVWRDADPPSTMDKLLKWAHCLIVYFIPCNVFLVTN
SAIILRLRKRGQRGLRPLVSKSTAILLGVTSLFALLWAPRIIVMLYHLYVAPVHRDWRVH
LALDIANMLAMLNTEVNFGLYCFISKTFRATVRQVICDVHMACALKSQPKQTVVELMLKS
VGTEL
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| BDBM50390577 |
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| n/a |
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| Name | BDBM50390577 |
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| Synonyms: | CHEMBL2069482 |
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| Type | Small organic molecule |
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| Emp. Form. | C19H18N4O2 |
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| Mol. Mass. | 334.3718 |
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| SMILES | N[C@@H](Cc1ccccc1)C(=O)Nc1cc(c[nH]c1=O)-c1ccncc1 |r| |
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| Structure | 
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