| Reaction Details |
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 | Report a problem with these data |
| Target | Fatty-acid amide hydrolase 1 [30-579] |
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| Ligand | BDBM50414260 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_571759 (CHEMBL1033004) |
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| IC50 | 251188.64±n/a nM |
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| Citation |  Wyffels, L; Muccioli, GG; De Bruyne, S; Moerman, L; Sambre, J; Lambert, DM; De Vos, F Synthesis, in vitro and in vivo evaluation, and radiolabeling of aryl anandamide analogues as candidate radioligands for in vivo imaging of fatty acid amide hydrolase in the brain. J Med Chem52:4613-22 (2009) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Fatty-acid amide hydrolase 1 [30-579] |
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| Name: | Fatty-acid amide hydrolase 1 [30-579] |
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| Synonyms: | Anandamide amidohydrolase 1 | FAAH1_RAT | Faah | Faah1 | Fatty Acid Amide Hydrolase | Fatty Acid Amide Hydrolic, FAAH | Fatty-acid amide hydrolase (FAAH) | Fatty-acid amide hydrolase 1 | Fatty-acid amide hydrolase 1 (FAAH) | Fatty-acid amide hydrolase 1 (aa 30-579) | Oleamide hydrolase 1 |
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| Type: | Single-pass membrane protein; homodimer |
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| Mol. Mass.: | 60474.00 |
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| Organism: | Rattus norvegicus (rat) |
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| Description: | P97612 (aa 30-579) |
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| Residue: | 550 |
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| Sequence: | RWTGRQKARGAATRARQKQRASLETMDKAVQRFRLQNPDLDSEALLTLPLLQLVQKLQSG
ELSPEAVFFTYLGKAWEVNKGTNCVTSYLTDCETQLSQAPRQGLLYGVPVSLKECFSYKG
HDSTLGLSLNEGMPSESDCVVVQVLKLQGAVPFVHTNVPQSMLSFDCSNPLFGQTMNPWK
SSKSPGGSSGGEGALIGSGGSPLGLGTDIGGSIRFPSAFCGICGLKPTGNRLSKSGLKGC
VYGQTAVQLSLGPMARDVESLALCLKALLCEHLFTLDPTVPPLPFREEVYRSSRPLRVGY
YETDNYTMPSPAMRRALIETKQRLEAAGHTLIPFLPNNIPYALEVLSAGGLFSDGGRSFL
QNFKGDFVDPCLGDLILILRLPSWFKRLLSLLLKPLFPRLAAFLNSMRPRSAEKLWKLQH
EIEMYRQSVIAQWKAMNLDVLLTPMLGPALDLNTPGRATGAISYTVLYNCLDFPAGVVPV
TTVTAEDDAQMELYKGYFGDIWDIILKKAMKNSVGLPVAVQCVALPWQEELCLRFMREVE
QLMTPQKQPS
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| BDBM50414260 |
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| n/a |
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| Name | BDBM50414260 |
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| Synonyms: | CHEMBL560499 |
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| Type | Small organic molecule |
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| Emp. Form. | C28H40INO |
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| Mol. Mass. | 533.5278 |
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| SMILES | CCCCC\C=C/C\C=C/C\C=C/C\C=C/CCCC(=O)NCCc1ccccc1I |
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| Structure | 
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