| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Cyclin-dependent kinase 4 |
|---|
| Ligand | BDBM81346 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_51159 (CHEMBL666107) |
|---|
| IC50 | >10000±n/a nM |
|---|
| Citation |  Brown, GR; Bamford, AM; Bowyer, J; James, DS; Rankine, N; Tang, E; Torr, V; Culbert, EJ Naphthyl ketones: a new class of Janus kinase 3 inhibitors. Bioorg Med Chem Lett10:575-9 (2000) [PubMed] |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Cyclin-dependent kinase 4 |
|---|
| Name: | Cyclin-dependent kinase 4 |
|---|
| Synonyms: | CDK4 | CDK4_HUMAN | Cell division protein kinase 4 | Cyclin-dependent kinase 4 (CDK 4) | PSK-J3 |
|---|
| Type: | Enzyme Subunit |
|---|
| Mol. Mass.: | 33731.96 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P11802 |
|---|
| Residue: | 303 |
|---|
| Sequence: | MATSRYEPVAEIGVGAYGTVYKARDPHSGHFVALKSVRVPNGGGGGGGLPISTVREVALL
RRLEAFEHPNVVRLMDVCATSRTDREIKVTLVFEHVDQDLRTYLDKAPPPGLPAETIKDL
MRQFLRGLDFLHANCIVHRDLKPENILVTSGGTVKLADFGLARIYSYQMALTPVVVTLWY
RAPEVLLQSTYATPVDMWSVGCIFAEMFRRKPLFCGNSEADQLGKIFDLIGLPPEDDWPR
DVSLPRGAFPPRGPRPVQSVVPEMEESGAQLLLEMLTFNPHKRISAFRALQHSYLHKDEG
NPE
|
|
|
|---|
| BDBM81346 |
|---|
| n/a |
|---|
| Name | BDBM81346 |
|---|
| Synonyms: | CHEMBL538798 | M9440 (Me-3,4-dephostatin) |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C23H25NO |
|---|
| Mol. Mass. | 331.4507 |
|---|
| SMILES | CC(C)N(CCC(=O)c1ccc2ccccc2c1)Cc1ccccc1 |
|---|
| Structure | 
|
|---|
Search and Browse
