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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Sodium- and chloride-dependent glycine transporter 2 | ||
| Ligand | BDBM50439745 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEMBL_980598 (CHEMBL2423115) | ||
| IC50 | 700±n/a nM | ||
| Citation |  Sugane, T; Tobe, T; Hamaguchi, W; Shimada, I; Maeno, K; Miyata, J; Suzuki, T; Kimizuka, T; Sakamoto, S; Tsukamoto, S Atropisomeric 4-phenyl-4H-1,2,4-triazoles as selective glycine transporter 1 inhibitors. J Med Chem56:5744-56 (2014) [PubMed] Article | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Sodium- and chloride-dependent glycine transporter 2 | |||
| Name: | Sodium- and chloride-dependent glycine transporter 2 | ||
| Synonyms: | Glycine transporter 2 | Glyt2 | SC6A5_RAT | Slc6a5 | ||
| Type: | PROTEIN | ||
| Mol. Mass.: | 87845.43 | ||
| Organism: | Rattus norvegicus | ||
| Description: | ChEMBL_980598 | ||
| Residue: | 799 | ||
| Sequence: |
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| BDBM50439745 | |||
| n/a | |||
| Name | BDBM50439745 | ||
| Synonyms: | CHEMBL2419423 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C23H21N3 | ||
| Mol. Mass. | 339.4329 | ||
| SMILES | CCc1nnc(-c2ccc(cc2)-c2ccccc2)n1-c1ccccc1C |(36.18,-5.89,;34.91,-6.76,;33.52,-6.09,;33.04,-4.63,;31.5,-4.63,;31.03,-6.1,;29.7,-6.86,;28.37,-6.08,;27.03,-6.84,;27.02,-8.38,;28.36,-9.16,;29.69,-8.39,;25.69,-9.14,;24.36,-8.36,;23.02,-9.12,;23.01,-10.66,;24.35,-11.44,;25.68,-10.67,;32.28,-7,;32.28,-8.54,;30.95,-9.31,;30.95,-10.85,;32.29,-11.63,;33.62,-10.85,;33.62,-9.3,;34.95,-8.53,)| | ||
| Structure | 
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