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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Sodium- and chloride-dependent glycine transporter 2 | ||
| Ligand | BDBM50439751 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEMBL_980598 (CHEMBL2423115) | ||
| IC50 | 1600±n/a nM | ||
| Citation |  Sugane, T; Tobe, T; Hamaguchi, W; Shimada, I; Maeno, K; Miyata, J; Suzuki, T; Kimizuka, T; Sakamoto, S; Tsukamoto, S Atropisomeric 4-phenyl-4H-1,2,4-triazoles as selective glycine transporter 1 inhibitors. J Med Chem56:5744-56 (2014) [PubMed] Article | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Sodium- and chloride-dependent glycine transporter 2 | |||
| Name: | Sodium- and chloride-dependent glycine transporter 2 | ||
| Synonyms: | Glycine transporter 2 | Glyt2 | SC6A5_RAT | Slc6a5 | ||
| Type: | PROTEIN | ||
| Mol. Mass.: | 87845.43 | ||
| Organism: | Rattus norvegicus | ||
| Description: | ChEMBL_980598 | ||
| Residue: | 799 | ||
| Sequence: |
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| BDBM50439751 | |||
| n/a | |||
| Name | BDBM50439751 | ||
| Synonyms: | CHEMBL2419444 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C20H15FN4 | ||
| Mol. Mass. | 330.3583 | ||
| SMILES | Cc1nnc(-c2ccc(cc2)-c2ccccn2)n1-c1ccccc1F |(16.51,-26.63,;15.04,-26.16,;14.56,-24.69,;13.02,-24.7,;12.55,-26.16,;11.22,-26.92,;9.89,-26.14,;8.55,-26.9,;8.54,-28.44,;9.88,-29.22,;11.21,-28.46,;7.21,-29.2,;5.88,-28.42,;4.54,-29.18,;4.53,-30.73,;5.87,-31.5,;7.2,-30.74,;13.8,-27.07,;13.8,-28.6,;12.47,-29.38,;12.47,-30.92,;13.8,-31.69,;15.14,-30.92,;15.14,-29.37,;16.47,-28.59,)| | ||
| Structure | 
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