| Reaction Details |
|---|
 | Report a problem with these data |
| Target | G-protein coupled receptor 52 |
|---|
| Ligand | BDBM50022156 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_1367592 |
|---|
| EC50 | 35±n/a nM |
|---|
| Citation |  Setoh, M; Ishii, N; Kono, M; Miyanohana, Y; Shiraishi, E; Harasawa, T; Ota, H; Odani, T; Kanzaki, N; Aoyama, K; Hamada, T; Kori, M Discovery of the first potent and orally available agonist of the orphan G-protein-coupled receptor 52. J Med Chem57:5226-37 (2014) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| G-protein coupled receptor 52 |
|---|
| Name: | G-protein coupled receptor 52 |
|---|
| Synonyms: | GPR52 | GPR52_HUMAN | Probable G-protein coupled receptor 52 |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 41366.15 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | ChEMBL_108391 |
|---|
| Residue: | 361 |
|---|
| Sequence: | MNESRWTEWRILNMSSGIVNVSERHSCPLGFGHYSVVDVCIFETVVIVLLTFLIIAGNLT
VIFVFHCAPLLHHYTTSYFIQTMAYADLFVGVSCLVPTLSLLHYSTGVHESLTCQVFGYI
ISVLKSVSMACLACISVDRYLAITKPLSYNQLVTPCRLRICIILIWIYSCLIFLPSFFGW
GKPGYHGDIFEWCATSWLTSAYFTGFIVCLLYAPAAFVVCFTYFHIFKICRQHTKEINDR
RARFPSHEVDSSRETGHSPDRRYAMVLFRITSVFYMLWLPYIIYFLLESSRVLDNPTLSF
LTTWLAISNSFCNCVIYSLSNSVFRLGLRRLSETMCTSCMCVKDQEAQEPKPRKRANSCS
I
|
|
|
|---|
| BDBM50022156 |
|---|
| n/a |
|---|
| Name | BDBM50022156 |
|---|
| Synonyms: | CHEMBL3299120 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C25H20F3NO3 |
|---|
| Mol. Mass. | 439.4264 |
|---|
| SMILES | OCCNC(=O)c1cccc(c1)-c1cccc2cc(Cc3cccc(c3)C(F)(F)F)oc12 |
|---|
| Structure | 
|
|---|
Search and Browse
