Reaction Details |
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Target | Free fatty acid receptor 4 |
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Ligand | BDBM50044874 |
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Substrate/Competitor | n/a |
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Meas. Tech. | ChEMBL_1454435 (CHEMBL3365231) |
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IC50 | 7.9±n/a nM |
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Citation | Sparks, SM; Chen, G; Collins, JL; Danger, D; Dock, ST; Jayawickreme, C; Jenkinson, S; Laudeman, C; Leesnitzer, MA; Liang, X; Maloney, P; McCoy, DC; Moncol, D; Rash, V; Rimele, T; Vulimiri, P; Way, JM; Ross, S Identification of diarylsulfonamides as agonists of the free fatty acid receptor 4 (FFA4/GPR120). Bioorg Med Chem Lett24:3100-3 (2014) [PubMed] Article |
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More Info.: | Get all data from this article, Assay Method |
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Free fatty acid receptor 4 |
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Name: | Free fatty acid receptor 4 |
Synonyms: | FFAR4_MOUSE | Ffar4 | Free fatty acid receptor 4 | G-protein coupled receptor GT01 | Gpr120 | O3far1 | Omega-3 fatty acid receptor 1 |
Type: | PROTEIN |
Mol. Mass.: | 40828.60 |
Organism: | Mus musculus |
Description: | ChEMBL_1454435 |
Residue: | 361 |
Sequence: | MSPECAQTTGPGPSHTLDQVNRTHFPFFSDVKGDHRLVLSVVETTVLGLIFVVSLLGNVC
ALVLVARRRRRGATASLVLNLFCADLLFTSAIPLVLVVRWTEAWLLGPVVCHLLFYVMTM
SGSVTILTLAAVSLERMVCIVRLRRGLSGPGRRTQAALLAFIWGYSALAALPLCILFRVV
PQRLPGGDQEIPICTLDWPNRIGEISWDVFFVTLNFLVPGLVIVISYSKILQITKASRKR
LTLSLAYSESHQIRVSQQDYRLFRTLFLLMVSFFIMWSPIIITILLILIQNFRQDLVIWP
SLFFWVVAFTFANSALNPILYNMSLFRNEWRKIFCCFFFPEKGAIFTDTSVRRNDLSVIS
S
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BDBM50044874 |
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n/a |
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Name | BDBM50044874 |
Synonyms: | CHEMBL3311302 |
Type | Small organic molecule |
Emp. Form. | C20H17NO3S |
Mol. Mass. | 351.419 |
SMILES | Cc1ccc(cc1)S(=O)(=O)NC1c2ccccc2Oc2ccccc12 |
Structure |
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