| Reaction Details |
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 | Report a problem with these data |
| Target | Free fatty acid receptor 1 |
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| Ligand | BDBM50138174 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1549475 (CHEMBL3755626) |
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| EC50 | 112±n/a nM |
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| Citation |  Ma, Z; Lin, DC; Sharma, R; Liu, J; Zhu, L; Li, AR; Kohn, T; Wang, Y; Liu, JJ; Bartberger, MD; Medina, JC; Zhuang, R; Li, F; Zhang, J; Luo, J; Wong, S; Tonn, GR; Houze, JB Discovery of the imidazole-derived GPR40 agonist AM-3189. Bioorg Med Chem Lett26:15-20 (2015) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Free fatty acid receptor 1 |
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| Name: | Free fatty acid receptor 1 |
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| Synonyms: | FFAR1 | FFAR1_HUMAN | G-protein Coupled Receptor 40 | GPR40 |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 31473.32 |
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| Organism: | Homo sapiens (Human) |
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| Description: | O14842 |
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| Residue: | 300 |
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| Sequence: | MDLPPQLSFGLYVAAFALGFPLNVLAIRGATAHARLRLTPSLVYALNLGCSDLLLTVSLP
LKAVEALASGAWPLPASLCPVFAVAHFFPLYAGGGFLAALSAGRYLGAAFPLGYQAFRRP
CYSWGVCAAIWALVLCHLGLVFGLEAPGGWLDHSNTSLGINTPVNGSPVCLEAWDPASAG
PARFSLSLLLFFLPLAITAFCYVGCLRALARSGLTHRRKLRAAWVAGGALLTLLLCVGPY
NASNVASFLYPNLGGSWRKLGLITGAWSVVLNPLVTGYLGRGPGLKTVCAARTQGGKSQK
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| BDBM50138174 |
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| n/a |
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| Name | BDBM50138174 |
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| Synonyms: | CHEMBL3754173 |
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| Type | Small organic molecule |
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| Emp. Form. | C27H23F3N2O4 |
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| Mol. Mass. | 496.4777 |
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| SMILES | Cn1ccnc1[C@@H](CC(O)=O)c1ccc(OCc2cccc(c2)-c2ccccc2OC(F)(F)F)cc1 |r| |
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| Structure | 
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