| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Oxytocin receptor |
|---|
| Ligand | BDBM35714 |
|---|
| Substrate/Competitor | n/a |
|---|
| Ki | 1550±n/a nM |
|---|
| Comments | PDSP_1416 |
|---|
| Citation |  Tahara, A; Tomura, Y; Wada, KI; Kusayama, T; Tsukada, J; Takanashi, M; Yatsu, T; Uchida, W; Tanaka, A Pharmacological profile of YM087, a novel potent nonpeptide vasopressin V1A and V2 receptor antagonist, in vitro and in vivo. J Pharmacol Exp Ther282:301-8 (1997) [PubMed] |
|---|
| More Info.: | Get all data from this article |
|---|
| |
| Oxytocin receptor |
|---|
| Name: | Oxytocin receptor |
|---|
| Synonyms: | OT-R | OXYR_RAT | Otr | Oxtr | Oxytocin |
|---|
| Type: | Enzyme Catalytic Domain |
|---|
| Mol. Mass.: | 42889.28 |
|---|
| Organism: | RAT |
|---|
| Description: | Oxytocin OXTR RAT::P70536 |
|---|
| Residue: | 388 |
|---|
| Sequence: | MEGTPAANWSVELDLGSGVPPGEEGNRTAGPPQRNEALARVEVAVLCLILFLALSGNACV
LLALRTTRHKHSRLFFFMKHLSIADLVVAVFQVLPQLLWDITFRFYGPDLLCRLVKYLQV
VGMFASTYLLLLMSLDRCLAICQPLRSLRRRTDRLAVLGTWLGCLVASAPQVHIFSLREV
ADGVFDCWAVFIQPWGPKAYVTWITLAVYIVPVIVLAACYGLISFKIWQNLRLKTAAAAA
AAEGNDAAGGAGRAALARVSSVKLISKAKIRTVKMTFIIVLAFIVCWTPFFFVQMWSVWD
VNAPKEASAFIIAMLLASLNSCCNPWIYMLFTGHLFHELVQRFFCCSARYLKGSRPGETS
VSKKSNSSTFVLSRRSSSQRSCSQPSSA
|
|
|
|---|
| BDBM35714 |
|---|
| n/a |
|---|
| Name | BDBM35714 |
|---|
| Synonyms: | CHEMBL420762 | Mozavaptan | N-[4-(5-Dimethylamino-2,3,4,5-tetrahydro-benzo[b]azepine-1-carbonyl)-phenyl]-2-methyl-benzamide | OPC-31260 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C27H29N3O2 |
|---|
| Mol. Mass. | 427.5381 |
|---|
| SMILES | CN(C)C1CCCN(C(=O)c2ccc(NC(=O)c3ccccc3C)cc2)c2ccccc12 |
|---|
| Structure | 
|
|---|
Search and Browse
