| Reaction Details |
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 | Report a problem with these data |
| Target | Prolyl hydroxylase EGLN3 |
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| Ligand | BDBM107704 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Mass Spectrometry Assay |
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| Temperature | 298.15±n/a K |
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| IC50 | 390±n/a nM |
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| Comments | extracted |
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| Citation |  Kawamoto, RM; Wu, S; Evdokimov, AG; Greis, KD; Boyer, AS; Warshakoon, NC Prolyl hydroxylase inhibitors and method of use US Patent US8722895 Publication Date 5/13/2014 |
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| More Info.: | Get all data from this article, Assay Method |
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| Prolyl hydroxylase EGLN3 |
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| Name: | Prolyl hydroxylase EGLN3 |
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| Synonyms: | EGLN3 | EGLN3_HUMAN | Egl nine homolog 3 (EGLIN3) | Egl nine homolog 3 (EGLN3) |
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| Type: | Protein |
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| Mol. Mass.: | 27265.54 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Q9H6Z9 |
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| Residue: | 239 |
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| Sequence: | MPLGHIMRLDLEKIALEYIVPCLHEVGFCYLDNFLGEVVGDCVLERVKQLHCTGALRDGQ
LAGPRAGVSKRHLRGDQITWIGGNEEGCEAISFLLSLIDRLVLYCGSRLGKYYVKERSKA
MVACYPGNGTGYVRHVDNPNGDGRCITCIYYLNKNWDAKLHGGILRIFPEGKSFIADVEP
IFDRLLFFWSDRRNPHEVQPSYATRYAMTVWYFDAEERAEAKKKFRNLTRKTESALTED
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| BDBM107704 |
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| n/a |
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| Name | BDBM107704 |
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| Synonyms: | US11426393, Compound Table XV.11 | US8598210, 119 | US8598210, Table XV, 10 | US8598210, Table XV, 11 | US8722895, 10: {[5-(3-Chlorophenyl)-3-hydroxypyridine-2- carbonyl]amino}-acetic acid trifluoroacetic acid salt | US8722895, 11: {[5-(3-Chlorophenyl)-3-hydroxypyridine-2- carbonyl]amino}-acetic acid | US9598370, Example 00136 | USRE47437, Example {[5-(3-Chlorophenyl)-3-hydroxypyridine-2-carbonyl]amino}-acetic acid |
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| Type | Small organic molecule |
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| Emp. Form. | C14H11ClN2O4 |
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| Mol. Mass. | 306.701 |
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| SMILES | OC(=O)CNC(=O)c1ncc(cc1O)-c1cccc(Cl)c1 |
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| Structure | 
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