Reaction Details | |||
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Target | Non-receptor tyrosine-protein kinase TYK2 | ||
Ligand | BDBM153663 | ||
Substrate/Competitor | n/a | ||
Meas. Tech. | Inhibition Assay | ||
pH | 7.2±n/a | ||
Ki | 5.6±n/a nM | ||
Comments | extracted | ||
Citation | ![]() | ||
More Info.: | Get all data from this article, Assay Method | ||
Non-receptor tyrosine-protein kinase TYK2 | |||
Name: | Non-receptor tyrosine-protein kinase TYK2 | ||
Synonyms: | Non-receptor tyrosine-protein kinase TYK2 (TYK2) | TYK2 | TYK2_HUMAN | Tyrosine-protein kinase TYK2 | ||
Type: | Protein | ||
Mol. Mass.: | 133666.03 | ||
Organism: | Homo sapiens (Human) | ||
Description: | P29597 | ||
Residue: | 1187 | ||
Sequence: |
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BDBM153663 | |||
n/a | |||
Name | BDBM153663 | ||
Synonyms: | US8999998, 109 | ||
Type | Small organic molecule | ||
Emp. Form. | C19H17ClN6O3 | ||
Mol. Mass. | 412.83 | ||
SMILES | COc1ccc(Cl)cc1-c1c(NC(=O)c2cnn3cccnc23)cnn1CCO |(1.2,-5.39,;.43,-4.06,;1.2,-2.73,;2.74,-2.73,;3.51,-1.39,;2.74,-.06,;3.51,1.27,;1.2,-.06,;.43,-1.39,;-1.11,-1.39,;-2.02,-.15,;-1.25,1.19,;-2.02,2.52,;-3.51,2.12,;-1.25,3.85,;-2.15,5.1,;-1.25,6.35,;.22,5.87,;1.55,6.64,;2.88,5.87,;2.88,4.33,;1.55,3.56,;.22,4.33,;-3.48,-.62,;-3.48,-2.16,;-2.02,-2.64,;-1.25,-3.97,;-2.02,-5.31,;-1.25,-6.64,)| | ||
Structure | ![]() |