| Reaction Details |
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 | Report a problem with these data |
| Target | Histone H3.1 [22-45] |
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| Ligand | BDBM155255 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Wild-Type and Mutant PRC2 Enzyme Assays |
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| IC50 | 104±0 nM |
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| Citation |  Kuntz, KW; Campbell, JE; Seki, M Substituted benzene compounds US Patent US10098888 Publication Date 10/16/2018 |
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| More Info.: | Get all data from this article, Assay Method |
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| Histone H3.1 [22-45] |
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| Name: | Histone H3.1 [22-45] |
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| Synonyms: | H31_HUMAN | H3C1 | H3FA | H3FB | H3FC HIST1H3C | H3FD | H3FF | H3FH | H3FI | H3FJ | H3FK | H3FL | H3K27me3 | HIST1H3A | HIST1H3B | HIST1H3D | HIST1H3E | HIST1H3F | HIST1H3G | HIST1H3H | HIST1H3I | HIST1H3J |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 2513.44 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P68431[22-45] |
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| Residue: | 24 |
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| Sequence: | |
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| BDBM155255 |
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| n/a |
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| Name | BDBM155255 |
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| Synonyms: | US10098888, Compound 105 | US11642348, Compound 105 | US9006242, 105 |
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| Type | Small organic molecule |
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| Emp. Form. | C31H42N4O3 |
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| Mol. Mass. | 518.6902 |
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| SMILES | CCN(C1CCOCC1)c1cc(cc(C(=O)NCc2c(C)cc(C)[nH]c2=O)c1C)C#CC1CCN(C)CC1 |
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| Structure | 
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