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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Nociceptin receptor | ||
| Ligand | BDBM239907 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | Binding Assay | ||
| pH | 7.4±n/a | ||
| Ki | 115±n/a nM | ||
| Comments | extracted | ||
| Citation |  Nolte, B; Schröder, W; Linz, K; Englberger, W; Schick, H; Graubaum, H; Braun, B; Ozegowski, S; Bálint, J; Sonnenschein, H Substituted 4-aminocyclohexane derivatives US Patent US9403767 Publication Date 8/2/2016 | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Nociceptin receptor | |||
| Name: | Nociceptin receptor | ||
| Synonyms: | KOR-3 | Kappa-type 3 opioid receptor | Mu-type opioid receptor (Mu) | NOP | Nociceptin Receptor (ORL1 Receptor) | Nociceptin receptor (NOP) | Nociceptin receptor (ORL-1) | Nociceptin receptor (ORL1) | Nociceptin/Orphanin FQ, NOP receptor | OOR | OPIATE ORL-1 | OPRL1 | OPRL1 protein | OPRX_HUMAN | ORL1 | ORL1 receptor | Opioid receptor like-1 | Orphanin FQ receptor | Orphanin FQ receptor (ORL1) | P41146 | ||
| Type: | G Protein-Coupled Receptor (GPCR) | ||
| Mol. Mass.: | 40702.87 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | P41146 | ||
| Residue: | 370 | ||
| Sequence: |
| ||
| BDBM239907 | |||
| n/a | |||
| Name | BDBM239907 | ||
| Synonyms: | US9403767, 72 | US9403767, 73 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C23H29F3N2 | ||
| Mol. Mass. | 390.485 | ||
| SMILES | CN(C)C1(CCC(CC1)(N(C)C)c1ccc(cc1)C(F)(F)F)c1ccccc1 |(-1.65,-6.62,;-.11,-6.57,;-.22,-8.11,;.61,-5.21,;1.94,-4.44,;1.94,-2.9,;.61,-2.13,;-.72,-2.9,;-.72,-4.44,;1.33,-.77,;1.44,.77,;2.87,-.72,;-.11,-.77,;-1.65,-.72,;-2.37,.64,;-1.56,1.95,;-.02,1.9,;.7,.54,;-2.28,3.31,;-3,4.67,;-3.64,2.59,;-.92,4.03,;1.33,-6.57,;2.87,-6.62,;3.6,-7.98,;2.78,-9.29,;1.24,-9.24,;.52,-7.88,)| | ||
| Structure | 
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