Reaction Details |
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Target | Nociceptin receptor |
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Ligand | BDBM302115 |
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Substrate/Competitor | n/a |
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Meas. Tech. | In Vitro Delta-Opioid Receptor Binding Assay |
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Ki | 27.7±0.4 nM |
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Citation | Tanaka, N; Yamawaki, K; Yao, J; Yu, J; Zhou, X Substituted benzimidazole-type piperidine compounds and uses thereof US Patent US9598411 Publication Date 3/21/2017 |
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More Info.: | Get all data from this article, Assay Method |
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Nociceptin receptor |
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Name: | Nociceptin receptor |
Synonyms: | KOR-3 | Kappa-type 3 opioid receptor | Mu-type opioid receptor (Mu) | NOP | Nociceptin Receptor (ORL1 Receptor) | Nociceptin receptor (NOP) | Nociceptin receptor (ORL-1) | Nociceptin receptor (ORL1) | Nociceptin/Orphanin FQ, NOP receptor | OOR | OPIATE ORL-1 | OPRL1 | OPRL1 protein | OPRX_HUMAN | ORL1 | ORL1 receptor | Opioid receptor like-1 | Orphanin FQ receptor | Orphanin FQ receptor (ORL1) | P41146 |
Type: | G Protein-Coupled Receptor (GPCR) |
Mol. Mass.: | 40702.87 |
Organism: | Homo sapiens (Human) |
Description: | P41146 |
Residue: | 370 |
Sequence: | MEPLFPAPFWEVIYGSHLQGNLSLLSPNHSLLPPHLLLNASHGAFLPLGLKVTIVGLYLA
VCVGGLLGNCLVMYVILRHTKMKTATNIYIFNLALADTLVLLTLPFQGTDILLGFWPFGN
ALCKTVIAIDYYNMFTSTFTLTAMSVDRYVAICHPIRALDVRTSSKAQAVNVAIWALASV
VGVPVAIMGSAQVEDEEIECLVEIPTPQDYWGPVFAICIFLFSFIVPVLVISVCYSLMIR
RLRGVRLLSGSREKDRNLRRITRLVLVVVAVFVGCWTPVQVFVLAQGLGVQPSSETAVAI
LRFCTALGYVNSCLNPILYAFLDENFKACFRKFCCASALRRDVQVSDRVRSIAKDVALAC
KTSETVPRPA
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BDBM302115 |
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n/a |
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Name | BDBM302115 |
Synonyms: | US9598411, Ref. No. ZA23 |
Type | Small organic molecule |
Emp. Form. | C32H46N4O |
Mol. Mass. | 502.7338 |
SMILES | CC(=O)C1CCN(Cc2nc3ccccc3n2[C@@H]2C[C@@H]3CCC[C@H](C2)N3[C@@H]2C[C@H]3CCC[C@H](C3)C2)CC1 |r,THB:26:25:17.18.24:20.22.21| |
Structure |
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