| Reaction Details |
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 | Report a problem with these data |
| Target | Homeobox protein PKNOX1 |
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| Ligand | BDBM514532 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | In Vitro Inhibition Assay |
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| IC50 | 49000±n/a nM |
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| Citation |  Bachovchin, WW; Lai, H; Wu, W Combination therapies using immuno-dash inhibitors and PGE2 antagonists US Patent US11096924 Publication Date 8/24/2021 |
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| More Info.: | Get all data from this article, Assay Method |
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| Homeobox protein PKNOX1 |
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| Name: | Homeobox protein PKNOX1 |
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| Synonyms: | Homeobox protein PREP-1 | PBX/knotted homeobox 1 | PKNOX1 | PKNX1_HUMAN | PREP1 |
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| Type: | Protein |
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| Mol. Mass.: | 47590.49 |
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| Organism: | Human |
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| Description: | P55347 |
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| Residue: | 436 |
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| Sequence: | MMATQTLSIDSYQDGQQMQVVTELKTEQDPNCSEPDAEGVSPPPVESQTPMDVDKQAIYR
HPLFPLLALLFEKCEQSTQGSEGTTSASFDVDIENFVRKQEKEGKPFFCEDPETDNLMVK
AIQVLRIHLLELEKVNELCKDFCSRYIACLKTKMNSETLLSGEPGSPYSPVQSQQIQSAI
TGTISPQGIVVPASALQQGNVAMATVAGGTVYQPVTVVTPQGQVVTQTLSPGTIRIQNSQ
LQLQLNQDLSILHQDDGSSKNKRGVLPKHATNVMRSWLFQHIGHPYPTEDEKKQIAAQTN
LTLLQVNNWFINARRRILQPMLDSSCSETPKTKKKTAQNRPVQRFWPDSIASGVAQPPPS
ELTMSEGAVVTITTPVNMNVDSLQSLSSDGATLAVQQVMMAGQSEDESVDSTEEDAGALA
PAHISGLVLENSDSLQ
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| BDBM514532 |
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| n/a |
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| Name | BDBM514532 |
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| Synonyms: | US11096924, DASH-inhibitors 3102 A | US11583516, Cmpd ID 3102A |
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| Type | Small organic molecule |
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| Emp. Form. | C16H27BN2O4 |
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| Mol. Mass. | 322.208 |
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| SMILES | N[C@H](C(=O)N1CCC[C@H]1B(O)O)C12CC3CC(CC(O)(C3)C1)C2 |r,TLB:1:12:20:16.15.17,22:12:20:16.15.17,15:16:21:20.14.13,THB:22:16:20:21.12.13,15:14:21:16.22.17| |
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| Structure | 
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