| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Metallo-beta-lactamase VIM-2 |
|---|
| Ligand | BDBM530709 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | Enzyme Activity: Determination of IC50 |
|---|
| IC50 | 4.04±n/a nM |
|---|
| Citation |  Pasternak, A; Dong, S; Scott, JD; Tang, H; Zhao, Z; Yang, D; Gu, X; Jiang, J; Xiao, L Metallo-beta-lactamase inhibitors and methods of use thereof US Patent US11207312 Publication Date 12/28/2021 |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Metallo-beta-lactamase VIM-2 |
|---|
| Name: | Metallo-beta-lactamase VIM-2 |
|---|
| Synonyms: | Beta-lactamase VIM-2 | Metallo-beta-lactamase VIM-2 (VIM-2) |
|---|
| Type: | Protein |
|---|
| Mol. Mass.: | 28318.00 |
|---|
| Organism: | Pseudomonas aeruginosa (g-Proteobacteria) |
|---|
| Description: | n/a |
|---|
| Residue: | 266 |
|---|
| Sequence: | MFKLLSKLLVYLTASIMAIASPLAFSVDSSGEYPTVSEIPVGEVRLYQIADGVWSHIATQ
SFDGAVYPSNGLIVRDGDELLLIDTAWGAKNTAALLAEIEKQIGLPVTRAVSTHFHDDRV
GGVDVLRAAGVATYASPSTRRLAEVEGNEIPTHSLEGLSSSGDAVRFGPVELFYPGAAHS
TDNLVVYVPSASVLYGGCAIYELSRTSAGNVADADLAEWPTSIERIQQHYPEAQFVIPGH
GLPGGLDLLKHTTNVVKAHTNRSVVE
|
|
|
|---|
| BDBM530709 |
|---|
| n/a |
|---|
| Name | BDBM530709 |
|---|
| Synonyms: | US11207312, Example 2 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C15H24FN9O5S2 |
|---|
| Mol. Mass. | 493.537 |
|---|
| SMILES | NC[C@@H](O)CNS(=O)(=O)c1ccc(N2CC[C@@H](N)[C@H](F)C2)c(-c2nn[nH]n2)c1S(N)(=O)=O |r| |
|---|
| Structure | 
|
|---|
Search and Browse
