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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Indoleamine 2,3-dioxygenase 1 | ||
| Ligand | BDBM541862 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | Enzymatic Assay | ||
| IC50 | 6.45±n/a nM | ||
| Citation |  Boss, C; Bur, D; Cren, S; Kimmerlin, T; Lotz-Jenne, C; Pothier, J; Tidten-Luksch, N Inhibitors of indoleamine 2,3-dioxygenase and/or tryptophan 2,3-dioxygenase US Patent US11267824 Publication Date 3/8/2022 | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Indoleamine 2,3-dioxygenase 1 | |||
| Name: | Indoleamine 2,3-dioxygenase 1 | ||
| Synonyms: | I23O1_HUMAN | IDO | IDO-1 | IDO1 | INDO | Indoleamine 2,3-Dioxygenasae (IDO) | Indoleamine 2,3-dioxygenase | Indoleamine-pyrrole 2,3-dioxygenase | ||
| Type: | Enzyme | ||
| Mol. Mass.: | 45330.80 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | P14902 | ||
| Residue: | 403 | ||
| Sequence: |
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| BDBM541862 | |||
| n/a | |||
| Name | BDBM541862 | ||
| Synonyms: | US11267824, Example 73a | ||
| Type | Small organic molecule | ||
| Emp. Form. | C21H24N2OS | ||
| Mol. Mass. | 352.493 | ||
| SMILES | O[C@H](C1CCC(CC1)c1ccccc1)c1c(sc2cncn12)C1CC1 |r,wD:1.0,(.55,-5.1,;-.48,-3.96,;-1.98,-4.28,;-2.46,-5.74,;-3.96,-6.06,;-4.99,-4.92,;-4.52,-3.45,;-3.01,-3.13,;-6.5,-5.24,;-6.98,-6.7,;-8.48,-7.02,;-9.51,-5.88,;-9.04,-4.41,;-7.53,-4.09,;,-2.49,;-.91,-1.25,;;1.46,-.48,;2.93,,;3.83,-1.25,;2.93,-2.49,;1.46,-2.02,;-2.45,-1.25,;-3.78,-2.02,;-3.78,-.48,)| | ||
| Structure | 
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