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TargetDipeptidyl peptidase 2
LigandBDBM142088
Substrate/Competitorn/a
Meas. Tech.EnPlex (purified enzyme activity assay)
IC50 0.200±n/a nM
Citation Bachovchin, WWLai, HWu, W Combination therapies using caspase-1 dependent anticancer agents and PGE2 antagonists US Patent US11559537 Publication Date 1/24/2023
More Info.:Get all data from this article,  Assay Method
 
Dipeptidyl peptidase 2
Name:Dipeptidyl peptidase 2
Synonyms:DAP II | DPP2 | DPP2_HUMAN | DPP7 | Dipeptidyl aminopeptidase II | Dipeptidyl peptidase 2 (DPP II) | Dipeptidyl peptidase 2 (DPP2) | Dipeptidyl peptidase II (DDP-II) | Dipeptidyl peptidase II (DPP II) | Dipeptidyl peptidase II (DPP2) | Dipeptidyl peptidase II and dipeptidyl peptidase IV (DPP2 and DPP4) | QPP | carboxytripeptidase | dipeptidyl arylamidase II | dipeptidyl(amino)peptidase II | dipeptidylarylamidase
Type:Protein
Mol. Mass.:54339.29
Organism:Homo sapiens (Human)
Description:Q9UHL4
Residue:492
Sequence:
MGSAPWAPVLLLALGLRGLQAGARRAPDPGFQERFFQQRLDHFNFERFGNKTFPQRFLVS
DRFWVRGEGPIFFYTGNEGDVWAFANNSAFVAELAAERGALLVFAEHRYYGKSLPFGAQS
TQRGHTELLTVEQALADFAELLRALRRDLGAQDAPAIAFGGSYGGMLSAYLRMKYPHLVA
GALAASAPVLAVAGLGDSNQFFRDVTADFEGQSPKCTQGVREAFRQIKDLFLQGAYDTVR
WEFGTCQPLSDEKDLTQLFMFARNAFTVLAMMDYPYPTDFLGPLPANPVKVGCDRLLSEA
QRITGLRALAGLVYNASGSEHCYDIYRLYHSCADPTGCGTGPDARAWDYQACTEINLTFA
SNNVTDMFPDLPFTDELRQRYCLDTWGVWPRPDWLLTSFWGGDLRAASNIIFSNGNLDPW
AGGGIRRNLSASVIAVTIQGGAHHLDLRASHPEDPASVVEARKLEATIIGEWVKAARREQ
QPALRGGPRLSL
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM142088
n/a
NameBDBM142088
Synonyms:US11096924, DASH-inhibitors 2243 | US11559537, Compound 2243 | US8933056, Ala-boroPro Thioxamide
TypeSmall organic molecule
Emp. Form.C7H15BN2O2S
Mol. Mass.202.082
SMILESC[C@H](N)C(=S)N1CCC[C@H]1B(O)O |r|
Structure
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