| Reaction Details |
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 | Report a problem with these data |
| Target | D(3) dopamine receptor |
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| Ligand | BDBM50527989 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | D3 Radioligand Binding Assay |
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| EC50 | 9.50±n/a nM |
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| Citation |  Sibley, DR; Moritz, AE; Free, RB; Steiner, JP; Southall, NT; Ferrer, M; Hu, X; Weiner, WS; Aubé, J; Frankowski, K Selective D3 dopamine receptor agonists and methods of their use US Patent US11634404 Publication Date 4/25/2023 |
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| More Info.: | Get all data from this article, Assay Method |
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| D(3) dopamine receptor |
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| Name: | D(3) dopamine receptor |
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| Synonyms: | DRD3 | DRD3_HUMAN | Dopamine D3 receptor |
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| Type: | PROTEIN |
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| Mol. Mass.: | 44213.40 |
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| Organism: | Homo sapiens |
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| Description: | ChEMBL_105671 |
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| Residue: | 400 |
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| Sequence: | MASLSQLSGHLNYTCGAENSTGASQARPHAYYALSYCALILAIVFGNGLVCMAVLKERAL
QTTTNYLVVSLAVADLLVATLVMPWVVYLEVTGGVWNFSRICCDVFVTLDVMMCTASILN
LCAISIDRYTAVVMPVHYQHGTGQSSCRRVALMITAVWVLAFAVSCPLLFGFNTTGDPTV
CSISNPDFVIYSSVVSFYLPFGVTVLVYARIYVVLKQRRRKRILTRQNSQCNSVRPGFPQ
QTLSPDPAHLELKRYYSICQDTALGGPGFQERGGELKREEKTRNSLSPTIAPKLSLEVRK
LSNGRLSTSLKLGPLQPRGVPLREKKATQMVAIVLGAFIVCWLPFFLTHVLNTHCQTCHV
SPELYSATTWLGYVNSALNPVIYTTFNIEFRKAFLKILSC
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| BDBM50527989 |
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| n/a |
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| Name | BDBM50527989 |
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| Synonyms: | CHEMBL4435730 | US11634404, Compound 82 |
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| Type | Small organic molecule |
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| Emp. Form. | C21H24N4O2 |
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| Mol. Mass. | 364.4409 |
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| SMILES | Cn1cc(C(=O)N2CCN(CCOc3cccnc3)CC2)c2ccccc12 |
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| Structure | 
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