| Reaction Details |
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 | Report a problem with these data |
| Target | Protein delta homolog 1 |
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| Ligand | BDBM637180 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | DLK Biochemical Assay |
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| IC50 | 5.80±n/a nM |
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| Citation |  Patel, A; Zack, D; Welsbie, D; Berlinicke, C; Lilley, BN; Kim, B; Schirok, H; Schubert, W; Koch, M; Nicolas, L; Terjung, C; Lobell, M; Holton, S; Jungmann, N SUBSTITUTED 4-([1,2,4]TRIAZOLO[1,5-a]PYRIDIN-6-YL)THIOPHENE-2-CARBOXAMIDE DERIVATIVES AND USE THEREOF US Patent US20230382904 Publication Date 11/30/2023 |
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| More Info.: | Get all data from this article, Assay Method |
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| Protein delta homolog 1 |
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| Name: | Protein delta homolog 1 |
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| Synonyms: | DLK | DLK-1 | DLK1 | DLK1_HUMAN | FA1 | Fetal antigen 1 | pG2 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 41294.81 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_1444684 |
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| Residue: | 383 |
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| Sequence: | MTATEALLRVLLLLLAFGHSTYGAECFPACNPQNGFCEDDNVCRCQPGWQGPLCDQCVTS
PGCLHGLCGEPGQCICTDGWDGELCDRDVRACSSAPCANNRTCVSLDDGLYECSCAPGYS
GKDCQKKDGPCVINGSPCQHGGTCVDDEGRASHASCLCPPGFSGNFCEIVANSCTPNPCE
NDGVCTDIGGDFRCRCPAGFIDKTCSRPVTNCASSPCQNGGTCLQHTQVSYECLCKPEFT
GLTCVKKRALSPQQVTRLPSGYGLAYRLTPGVHELPVQQPEHRILKVSMKELNKKTPLLT
EGQAICFTILGVLTSLVVLGTVGIVFLNKCETWVSNLRYNHMLRKKKNLLLQYNSGEDLA
VNIIFPEKIDMTTFSKEAGDEEI
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| BDBM637180 |
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| n/a |
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| Name | BDBM637180 |
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| Synonyms: | US20230382904, Compound 100 |
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| Type | Small organic molecule |
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| Emp. Form. | C24H23N7O4S |
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| Mol. Mass. | 505.549 |
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| SMILES | C[C@@H](CO)NC(=O)c1cc(cn2nc(N)nc12)-c1csc(c1)C(=O)N[C@@H](C)c1nc2ccccc2o1 |r| |
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| Structure | 
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