| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Amine oxidase [flavin-containing] B |
|---|
| Ligand | BDBM153684 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | MAO-A and MAO-B Assay |
|---|
| IC50 | >130000±n/a nM |
|---|
| Citation |  Cannizzaro, CE; Graupe, M; Guerrero, JA; Lu, Y; Strickley, RG; Venkataramani, C; Zablocki, J Compounds for the treatment of addiction US Patent US9610299 Publication Date 4/4/2017 |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Amine oxidase [flavin-containing] B |
|---|
| Name: | Amine oxidase [flavin-containing] B |
|---|
| Synonyms: | AOFB_HUMAN | MAO-B | MAOB | Monoamine oxidase type B | Monoamine oxidase type B (MAO B) | Monoamine oxidase type B (MAO B) | Monoamine oxidase type B (MAOB) |
|---|
| Type: | Protein |
|---|
| Mol. Mass.: | 58768.76 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P27338 |
|---|
| Residue: | 520 |
|---|
| Sequence: | MSNKCDVVVVGGGISGMAAAKLLHDSGLNVVVLEARDRVGGRTYTLRNQKVKYVDLGGSY
VGPTQNRILRLAKELGLETYKVNEVERLIHHVKGKSYPFRGPFPPVWNPITYLDHNNFWR
TMDDMGREIPSDAPWKAPLAEEWDNMTMKELLDKLCWTESAKQLATLFVNLCVTAETHEV
SALWFLWYVKQCGGTTRIISTTNGGQERKFVGGSGQVSERIMDLLGDRVKLERPVIYIDQ
TRENVLVETLNHEMYEAKYVISAIPPTLGMKIHFNPPLPMMRNQMITRVPLGSVIKCIVY
YKEPFWRKKDYCGTMIIDGEEAPVAYTLDDTKPEGNYAAIMGFILAHKARKLARLTKEER
LKKLCELYAKVLGSLEALEPVHYEEKNWCEEQYSGGCYTTYFPPGILTQYGRVLRQPVDR
IYFAGTETATHWSGYMEGAVEAGERAAREILHAMGKIPEDEIWQSEPESVDVPAQPITTT
FLERHLPSVPGLLRLIGLTTIFSATALGFLAHKRGLLVRV
|
|
|
|---|
| BDBM153684 |
|---|
| n/a |
|---|
| Name | BDBM153684 |
|---|
| Synonyms: | US10507215, Compound 1 | US9000015, 1 | US9610299, Example 1 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C22H20Cl2N2O4 |
|---|
| Mol. Mass. | 447.311 |
|---|
| SMILES | COCCOc1cc(Cl)c(C(=O)NCc2ccc(cc2)-c2cc[nH]c(=O)c2)c(Cl)c1 |
|---|
| Structure | 
|
|---|
Search and Browse
