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TargetIntermediate conductance calcium-activated potassium channel protein 4
LigandBDBM314321
Substrate/Competitorn/a
Meas. Tech.Electrophysiology Assay
IC50 62.0±n/a nM
Citation Green LWang H Oxazolidinone and imidazolidinone compounds US Patent  US9611232 Publication Date 4/4/2017
More Info.:Get all data from this article,  Assay Method
 
Intermediate conductance calcium-activated potassium channel protein 4
Name:Intermediate conductance calcium-activated potassium channel protein 4
Synonyms:IK1 | IKCa1 | KCa4 | Putative Gardos channel | SK4
Type:PROTEIN
Mol. Mass.:47723.22
Organism:Homo sapiens (Human)
Description:ChEMBL_1361891
Residue:427
Sequence:
MGGDLVLGLGALRRRKRLLEQEKSLAGWALVLAGTGIGLMVLHAEMLWFGGCSWALYLFL
VKCTISISTFLLLCLIVAFHAKEVQLFMTDNGLRDWRVALTGRQAAQIVLELVVCGLHPA
PVRGPPCVQDLGAPLTSPQPWPGFLGQGEALLSLAMLLRLYLVPRAVLLRSGVLLNASYR
SIGALNQVRFRHWFVAKLYMNTHPGRLLLGLTLGLWLTTAWVLSVAERQAVNATGHLSDT
LWLIPITFLTIGYGDVVPGTMWGKIVCLCTGVMGVCCTALLVAVVARKLEFNKAEKHVHN
FMMDIQYTKEMKESAARVLQEAWMFYKHTRRKESHAARRHQRKLLAAINAFRQVRLKHRK
LREQVNSMVDISKMHMILYDLQQNLSSSHRALEKQIDTLAGKLDALTELLSTALGPRQLP
EPSQQSK
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  Blast E-value cutoff:
BDBM314321
n/a
NameBDBM314321
Synonyms:US9611232, Example 32
TypeSmall organic molecule
Emp. Form.C20H17F4NO4
Mol. Mass.411.3469
SMILESCCOC(=O)CN1[C@@H]([C@@H](OC1=O)c1cccc(c1)C(F)(F)F)c1ccc(F)cc1 |r|
Structure
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